ReviewCurrent opinion in biotechnology2009
Protein engineering in designing tailored enzymes and microorganisms for biofuels production.
Review in Current opinion in biotechnology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Enhancing Production of Tryptophan via Cellulose Utilization by Escherichia coli.Applied biochemistry and biotechnology · 2026Article
- Harnessing Microbial Power for a Sustainable Future Food System.Microorganisms · 2025Review
- FACS-Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments.Advanced materials interfaces · 2025Article
- Thermophilic β-mannanases from bacteria: production, resources, structural features and bioengineering strategies.World journal of microbiology & biotechnology · 2024Review
- Experimental and computational studies of cellulases as bioethanol enzymes.Bioengineered · 2022Review
- Elucidating structure-performance relationships in whole-cell cooperative enzyme catalysis.Nature catalysis · 2019Article
- Ruminal metagenomic libraries as a source of relevant hemicellulolytic enzymes for biofuel production.Microbial biotechnology · 2018Article
- Effects of substrate binding site residue substitutions of xynA from Bacillus amyloliquefaciens on substrate specificity.BMC biotechnology · 2018Article
- US132 Cyclodextrin Glucanotransferase Engineering by Random Mutagenesis for an Anti-Staling Purpose.Molecular biotechnology · 2016Article
- Coexpression of cellulases in Pichia pastoris as a self-processing protein fusion.AMB Express · 2015Article
- Efficient Eucalypt Cell Wall Deconstruction and Conversion for Sustainable Lignocellulosic Biofuels.Frontiers in bioengineering and biotechnology · 2015Review
- Expression, isolation, and purification of soluble and insoluble biotinylated proteins for nerve tissue regeneration.Journal of visualized experiments : JoVE · 2014Article
- Directed evolution as a powerful synthetic biology tool.Methods (San Diego, Calif.) · 2013Article
- Article
- Improved activity of a thermophilic cellulase, Cel5A, from Thermotoga maritima on ionic liquid pretreated switchgrass.PloS one · 2013Article
- Tracing determinants of dual substrate specificity in glycoside hydrolase family 5.The Journal of biological chemistry · 2012Article
- Glycoside hydrolases from a targeted compost metagenome, activity-screening and functional characterization.BMC biotechnology · 2012Article
- Biocatalyst development by directed evolution.Bioresource technology · 2012Review
- Direct conversion of xylan to ethanol by recombinant Saccharomyces cerevisiae strains displaying an engineered minihemicellulosome.Applied and environmental microbiology · 2012Article
- Site-directed mutagenesis of a family 42 β-galactosidase from an antarctic bacterium.International journal of biochemistry and molecular biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Lignocellulosic biofuels represent a sustainable, renewable, and the only foreseeable alternative energy source to transportation fossil fuels. However, the recalcitrant nature of lignocellulose poses technical hurdles to an economically viable biorefinery. Low enzymatic hydrolysis efficiency and low productivity, yield, and titer of biofuels are among the top cost contributors. Protein engineering has been used to improve the performance of lignocellulose-degrading enzymes, as well as proteins involved in biofuel synthesis pathways. Unlike its great success seen in other industrial applications, protein engineering has achieved only modest results in improving the lignocellulose-to-biofuels efficiency. This review will discuss the unique challenges that protein engineering faces in the process of converting lignocellulose to biofuels and how they are addressed by recent advances in this field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.