ArticleBMC proceedings2009
Composition and biological significance of the human Nalpha-terminal acetyltransferases.
Article in BMC proceedings, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer.Journal for immunotherapy of cancer · 2024Article
- Article
- Characterisation and preliminary functional analysis of N-acetyltransferase 13 from Schistosoma japonicum.BMC veterinary research · 2021Article
- In Vitro N-Terminal Acetylation of Bacterially Expressed Parvalbumins by N-Terminal Acetyltransferases from Escherichia coli.Applied biochemistry and biotechnology · 2021Article
- HPO iron chelator, CP655, causes the G1/S phase cell cycle block via p21 upregulation.Immunity, inflammation and disease · 2020Article
- Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway.OncoTargets and therapy · 2019Article
- Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT).International journal of molecular sciences · 2016Review
- High expression of Naa10p associates with lymph node metastasis and predicts favorable prognosis of oral squamous cell carcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Review
- Structural basis for substrate-specific acetylation of Nα-acetyltransferase Ard1 from Sulfolobus solfataricus.Scientific reports · 2015Article
- A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome.Journal of medical genetics · 2014Article
- In silico identification and characterization of N-Terminal acetyltransferase genes of poplar (Populus trichocarpa).International journal of molecular sciences · 2014Article
- Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.Nature structural & molecular biology · 2013Article
- Exploring the accessible conformations of N-terminal acetylated α-synuclein.FEBS letters · 2013Review
- Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.Molecular & cellular proteomics : MCP · 2013Article
- Protein N-terminal acetyltransferases in cancer.Oncogene · 2013Review
- Mutation of an Arabidopsis NatB N-alpha-terminal acetylation complex component causes pleiotropic developmental defects.PloS one · 2013Article
- Structural organization of intercellular channels II. Amino terminal domain of the connexins: sequence, functional roles, and structure.Biochimica et biophysica acta · 2012Review
- Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features.Molecular & cellular proteomics : MCP · 2012Article
- Expression of human NAA11 (ARD1B) gene is tissue-specific and is regulated by DNA methylation.Epigenetics · 2011Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Protein Nalpha-terminal acetylation is one of the most common protein modifications in eukaryotic cells, occurring on approximately 80% of soluble human proteins. An increasing number of studies links Nalpha-terminal acetylation to cell differentiation, cell cycle, cell survival, and cancer. Thus, Nalpha-terminal acetylation is an essential modification for normal cell function in humans. Still, little is known about the functional role of Nalpha-terminal acetylation. Recently, the three major human N-acetyltransferase complexes, hNatA, hNatB and hNatC, were identified and characterized. We here summarize the identified N-terminal acetyltransferase complexes in humans, and we review the biological studies on Nalpha-terminal acetylation in humans and other higher eukaryotes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.