Evidence map›Paper›PMID 19659741›Full record

ReviewFEMS yeast research2009

Pichia stipitis genomics, transcriptomics, and gene clusters.

Thomas W Jeffries, Jennifer R Headman Van Vleet

Abstract readReview
In one paragraph

Review in FEMS yeast research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Production of Lactate by Metabolically EngineeredJournal of fungi (Basel, Switzerland) · 2025
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  4. Review
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  6. Article
  7. Comprehensive Characterization of MutantJournal of microbiology and biotechnology · 2022
    Article
  8. First report on Vitamin BBiotechnology for biofuels and bioproducts · 2022
    Article
  9. Article
  10. Article
  11. D-Xylose Sensing inInternational journal of molecular sciences · 2021
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas W JeffriesUSDA Forest Products Laboratory, Madison, WI 53705, USA.
Jennifer R Headman Van Vleet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome sequencing and subsequent global gene expression studies have advanced our understanding of the lignocellulose-fermenting yeast Pichia stipitis. These studies have provided an insight into its central carbon metabolism, and analysis of its genome has revealed numerous functional gene clusters and tandem repeats. Specialized physiological traits are often the result of several gene products acting together. When coinheritance is necessary for the overall physiological function, recombination and selection favor colocation of these genes in a cluster. These are particularly evident in strongly conserved and idiomatic traits. In some cases, the functional clusters consist of multiple gene families. Phylogenetic analyses of the members in each family show that once formed, functional clusters undergo duplication and differentiation. Genome-wide expression analysis reveals that regulatory patterns of clusters are similar after they have duplicated and that the expression profiles evolve along with functional differentiation of the clusters. Orthologous gene families appear to arise through tandem gene duplication, followed by differentiation in the regulatory and coding regions of the gene. Genome-wide expression analysis combined with cross-species comparisons of functional gene clusters should reveal many more aspects of eukaryotic physiology.

Indexed as

Gene Expression ProfilingGenes, FungalGenome, FungalMultigene FamilyEvolution, MolecularGene DuplicationPichiaRecombination, Genetic

Identifiers

PMID19659741
PMCPMC2784038

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.