ArticleThe New phytologist2009
Contribution of chromosomal polymorphisms to the G-matrix of Mimulus guttatus.
Article in The New phytologist, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Testing the evolutionary theory of inversion polymorphisms in the yellow monkeyflower (Mimulus guttatus).Nature communications · 2024Article
- The quantitative genetics of gene expression in Mimulus guttatus.PLoS genetics · 2024Article
- Experimental evolution suggests rapid assembly of the 'selfing syndrome' from standing variation inFrontiers in plant science · 2024Article
- Supergene potential of a selfish centromere.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Integrating genomics and multivariate evolutionary quantitative genetics: a case study of constraints on sexual selection inProceedings. Biological sciences · 2021Article
- Selfish chromosomal drive shapes recent centromeric histone evolution in monkeyflowers.PLoS genetics · 2021Article
- Extreme copy number variation at a tRNA ligase gene affecting phenology and fitness in yellow monkeyflowers.Molecular ecology · 2019Article
- Article
- Population structure and local selection yield high genomic variation in Mimulus guttatus.Molecular ecology · 2017Article
- Accessibility, constraint, and repetition in adaptive floral evolution.Developmental biology · 2016Review
- A Segregating Inversion Generates Fitness Variation in Yellow Monkeyflower (Mimulus guttatus).Genetics · 2016Article
- Centromere-associated meiotic drive and female fitness variation in Mimulus.Evolution; international journal of organic evolution · 2015Article
- Environmentally induced changes in correlated responses to selection reveal variable pleiotropy across a complex genetic network.Evolution; international journal of organic evolution · 2015Article
- Article
- Identifying the genes underlying quantitative traits: a rationale for the QTN programme.AoB PLANTS · 2014Article
- The genomic signal of partial sweeps in Mimulus guttatus.Genome biology and evolution · 2013Article
- Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci.Biology letters · 2011Article
- Interactions among flower-size QTL of Mimulus guttatus are abundant but highly variable in nature.Genetics · 2011Article
- Rapid evolution caused by pollinator loss in Mimulus guttatus.Evolution; international journal of organic evolution · 2011Article
- The genetics of inbreeding depression.Nature reviews. Genetics · 2009Review
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4 authors.
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Abstract
Evolution of genetic (co)variances (the G-matrix) fundamentally influences multitrait divergence. Here, we isolated the contribution of two chromosomal quantitative trait loci (QTLs), a meiotic drive locus and a polymorphic inversion, to the overall G-matrix for a suite of floral, phenological and male fitness traits in a population of Mimulus guttatus. This allowed us to predict the evolution of trait means and genetic (co)variances as a function of allele frequencies, and to evaluate theories about the maintenance of genetic variation in fitness. Individuals generated using a replicated F(2) breeding design were grown under common conditions, genotyped and measured for trait values. Significant additive genetic variance existed for all traits, and most genetic covariances were significantly nonzero. Both QTLs contribute to the additive genetic (co)variances of multiple traits. Pleiotropy was not generally consistent, either between QTLs or with the genetic background. Shifts in allele frequencies at either QTL are predicted to result in substantial changes in the G-matrix. Both QTLs contribute substantially to the genetic variation in pollen viability. The Drive QTL, and perhaps also the inversion, demonstrates the contribution of balancing selection to the maintenance of genetic variation in fitness.
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