ReviewOcular immunology and inflammation
Pathophysiology of retinal lymphoma.
Review in Ocular immunology and inflammation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 88 citations in OpenAlex.
- High-Dimensional Vitreous Proteomics Identifies Epigenetic Pathway Signatures in Vitreoretinal Lymphoma.Ophthalmology science · 2026Article
- Primary vitreoretinal lymphoma: diagnostic and therapeutic insights from a Slovenian population-based study.International journal of retina and vitreous · 2026Article
- Ocular Ultrasound as a Key to Diagnosing Uveitis-Masked Syndromes: Tips and Tricks.Clinics and practice · 2025Article
- Primary Intraocular Lymphoma: Rad-Path and Ophthalmologic Correlation.AJNR. American journal of neuroradiology · 2025Article
- Factors related to central nervous system involvement of primary vitreoretinal lymphoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Hyper-N-glycosylated SEL1L3 as auto-antigenic B-cell receptor target of primary vitreoretinal lymphomas.Scientific reports · 2024Article
- Case report: Intraretinal hyperflow microinfiltration lesions on swept-source optical coherence tomography angiography as a potential biomarker of primary vitreoretinal lymphoma.Frontiers in medicine · 2024Article
- Global collaboration of eye research: -personal experience.International journal of ophthalmology · 2024Article
- Electroretinographic and Optical Coherence Tomographic Evaluations of Eyes with Vitreoretinal Lymphoma.Journal of clinical medicine · 2023Article
- Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma.Ocular immunology and inflammation · 2023Observational
- Terson syndrome in reverse: intraventricular haemorrhage following primary intraocular haemorrhage.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- [Lymphoma of the eye and its adnexa : Modern pathological diagnostics and systemic treatment].Die Ophthalmologie · 2022Review
- Advanced OCT Analysis of Biopsy-proven Vitreoretinal Lymphoma.American journal of ophthalmology · 2022Article
- The molecular hallmarks of primary and secondary vitreoretinal lymphoma.Blood advances · 2022Article
- An explanation for Terson syndrome at last: the glymphatic reflux theory.Journal of neurology · 2022Review
- Relationship between vitreoretinal lymphoma and the site of lymphoma development in the central nervous system.Japanese journal of ophthalmology · 2022Article
- Comparative Molecular Analysis of Primary Central Nervous System Lymphomas and Matched Vitreoretinal Lymphomas by Vitreous Liquid Biopsy.International journal of molecular sciences · 2021Article
- Vitreoretinal Lymphoma.Cancers · 2021Review
- Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma.Scientific reports · 2020Article
- Combined cellular and soluble mediator analysis for improved diagnosis of vitreoretinal lymphoma.Acta ophthalmologica · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Retinal lymphoma, the most common form of intraocular lymphoma, is a high-grade malignancy, usually of B-cell type, and is associated with a poor prognosis because of frequent central nervous system (CNS) involvement. The neoplastic B-cells of retinal lymphoma have a characteristic morphology and immunophenotype, express certain chemokines and chemokine receptors, and produce interleukins (IL), e.g. IL-10. Together with the cytological features of these tumors, the immunophenotype, presence of immunoglobulin rearrangements, and biochemical profile aid the diagnosis of retinal lymphomas. Immunophenotyping and somatic mutation analysis suggest derivation of most retinal lymphomas from an early post-germinal centre B-cell. Chromosomal translocation data would suggest, however, that a subgroup of these neoplasms may arise from germinal centre B-cells, and these could be associated with a better prognosis. Further investigations, such as gene expression profiling, are required to identify oncogenic pathways potentially involved in retinal lymphoma development, and to identify new prognostic/therapeutic markers for this tumor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.