ReviewHuman genetics2009
Nature meets nurture: molecular genetics of gastric cancer.
Review in Human genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 2 syntheses or guidelines pooled it, 210 citations in OpenAlex.
- Gene-diet interactions in gastric cancer risk: a systematic review.World journal of gastroenterology · 2014Pooled it
- Role of EZH2 protein expression in gastric carcinogenesis among Asians: a meta-analysis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Pooled it
- LAPTM4B-35, a cancer-related gene, is associated with poor prognosis in TNM stages I-III gastric cancer patients.PloS one · 2015Trial
- Article
- Feasibility and Efficacy of Gastric Underwater Endoscopic Mucosal Resection.Diagnostics (Basel, Switzerland) · 2024Article
- Surface Markers for the Identification of Cancer Stem Cells.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Article
- Self-Renewal and Cancers of the Gastric Epithelium: An Update and the Role of the Lectin TFF1 as an Antral Tumor Suppressor.International journal of molecular sciences · 2022Review
- Evaluation ofArchives of Razi Institute · 2022Article
- MiR-711 regulates gastric cancer progression by targeting CD44.Cancer biomarkers : section A of Disease markers · 2022Article
- A Systematic Review of Artificial Intelligence Techniques in Cancer Prediction and Diagnosis.Archives of computational methods in engineering : state of the art reviews · 2022Review
- Status of CHEK2 and p53 in patients with early-onset and conventional gastric cancer.Oncology letters · 2021Article
- A Mouse Model of Helicobacter pylori Infection.Methods in molecular biology (Clifton, N.J.) · 2021Article
- TTK regulates proliferation and apoptosis of gastric cancer cells through the Akt-mTOR pathway.FEBS open bio · 2020Article
- Identifying specific miRNAs and associated mRNAs in CD44 and CD90 cancer stem cell subtypes in gastric cancer cell line SNU-5.International journal of clinical and experimental pathology · 2020Article
- lncRNA UCA1 Predicts a Poor Prognosis and Regulates Cell Proliferation and Migration by Repressing p21 and SPRY1 Expression in GC.Molecular therapy. Nucleic acids · 2019Article
- S100P is a molecular determinant of E-cadherin function in gastric cancer.Cell communication and signaling : CCS · 2019Article
- MTSS1 inhibits metastatic potential and induces G2/M phase cell cycle arrest in gastric cancer.OncoTargets and therapy · 2019Article
- MicroRNA-383-5p inhibits the progression of gastric carcinoma via targeting HDAC9 expression.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immensity of genes and molecules implicated in gastric carcinogenesis is overwhelming and the relevant importance of some of these molecules is too often unclear. This review serves to bring us up-to-date with the latest findings as well as to look at the larger picture in terms of how to tackle the problem of solving this multi-piece puzzle. In this review, the environmental nurturing of intestinal cancer is discussed, beginning with epidemiology (known causative factors for inducing molecular change), an update of H. pylori research, including the role of inflammation and stem cells in premalignant lesions. The role of E-cadherin in the nature (genotype) of diffuse gastric cancer is highlighted, and finally the ever growing discipline of SNP analysis (including IL1B) is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.