Evidence map›Paper›PMID 19657553›Full record

ArticleThe journal of nutrition, health & aging2009

Carla Task Force on Sarcopenia: propositions for clinical trials.

G Abellan van Kan, E André, H A Bischoff Ferrari, Y Boirie, G Onder, M Pahor, P Ritz, Y Rolland, C Sampaio, S Studenski and 2 more

Abstract read
In one paragraph

Article in The journal of nutrition, health & aging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Vitamin D Deficiency Treatment Patterns in Academic Urban Medical Center.The American journal of pharmacy benefits · 2014
    Article
  12. Article
  13. Pro-dromal sarcopenia.The journal of nutrition, health & aging · 2011
    Article
  14. Review
  15. Designing Phase II B trials in sarcopenia: the best target population.The journal of nutrition, health & aging · 2011
    Article
  16. Frailty: diagnosis and management.The journal of nutrition, health & aging · 2011
    Article
  17. Article
  18. Clinical practice in nursing homes as a key for progress.The journal of nutrition, health & aging · 2010
    Article
  19. Nutritional recommendations for the management of sarcopenia.Journal of the American Medical Directors Association · 2010
    Review
  20. Functional consequences of sarcopenia and dynapenia in the elderly.Current opinion in clinical nutrition and metabolic care · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

G Abellan van KanGérontopôle, INSERM U558, University of Toulouse III, Toulouse, France.
E André
H A Bischoff Ferrari
Y Boirie
G Onder
M Pahor
P Ritz
Y Rolland
C Sampaio
S Studenski
M Visser
B Vellas

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
NIA NIH HHS P30 AG024827NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

In the presence of an aging population, public health priorities need to evolve. As the populations gets older, the already existing pathologies have become commonplace with specific geriatric clinical syndromes like frailty, mobility disability, or cognitive impairment, among others. Sarcopenia is a good example for which geriatricians, neurologists, physiologists, nutritionists and epidemiologists need to find a consensual definition and diagnostic tool as well as guidelines for the management of clinical trials and possible treatments. The Carla Sarcopenia Task Force, which met in the south of France (Toulouse) for an expert consensus meeting called "Les Entretiens du Carla", have addressed a series of existing issues to place Sarcopenia into a nosological context: a definition which should be a composite of a change in muscle mass and a change in strength/function depending on either a progressive and chronic wasting process or an acute onset of loss of muscle mass; a recommendation for DXA and the Short Physical Performance Battery as a clinical pragmatic approach of Sarcopenia; a differentiated approach for clinical studies according to prevention or treatment objectives and depending on the sub-groups and target populations; and finally, a summary of therapeutic strategies currently recommended. The aim of "Les Entretiens du Carla", based on an expert meeting panel, was to address a series of unsolved issues in the field of Sarcopenia by combining the expert opinion with a revision of the existing literature on the topic. Through this report, the reader will appreciate the determination to find conclusions on the various issues and further studies to be developed to determine the best multidisciplinary approach needed.

Indexed as

Clinical Trials as TopicSarcopeniaAdvisory CommitteesAgedAgingFranceGeriatric AssessmentHumansMuscle, SkeletalMuscle Strength

Identifiers

PMID19657553
PMCPMC4311888

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.