Evidence map›Paper›PMID 19657044›Full record

ArticleThe Journal of clinical endocrinology and metabolism2009

The approach to the patient with paraganglioma.

Hartmut P H Neumann, Charis Eng

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 77 citations in OpenAlex.

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  12. Diagnosis of extra-adrenal phaeochromocytoma after nephrectomy.Central European journal of urology · 2014
    Article
  13. Management and follow up of extra-adrenal phaeochromocytoma.Central European journal of urology · 2014
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Hartmut P H NeumannDepartment of Nephrology and General Medicine, Section of Preventive Medicine, Albert-Ludwigs-University of Freiburg, Hugstetter Strasse 55, Freiburg, Germany. hartmut.neumann@uniklinik-freiburg.de
Charis Eng
Cleveland Clinic · USUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multidisciplinary management of patients with paragangliomas and pheochromocytomas remains challenging. The cornerstone of excellent multidisciplinary management of such patients is genetic classification and management in a tertiary care referral center. Up to one third of all symptomatic presentations of pheochromocytoma or paraganglioma are due to germline mutations in one of six genes defining multiple endocrine neoplasia type 2, von Hippel-Lindau disease, neurofibromatosis type 1, and the paraganglioma syndromes types 1, 3, and 4. This genetic classification forms the basis early diagnosis and follow-up including management of relatives. Easily available clinical information such as tumor location and number, age, gender, and family history must be used to prioritize which gene should be tested. Mutation carriers should undergo regular check-up to detect and treat metachronous paraganglial and extraparaganglial tumors, and depending on syndrome, other extraparaganglial neoplasias such as medullary thyroid cancer and renal clear cell carcinomas in time. Adrenal and extraadrenal retroperitoneal tumors should be operated by surgeons highly experienced in minimal invasive, endoscopic techniques.

Indexed as

Adrenal Gland NeoplasmsAdultGenes, Neurofibromatosis 1Germ-Line MutationHumansMaleMultiple Endocrine Neoplasia Type 2aParagangliomaPheochromocytomaSuccinate DehydrogenaseTerminology as TopicTomography, X-Ray ComputedVon Hippel-Lindau Tumor Suppressor ProteinSDHD protein, humanSuccinate DehydrogenaseVHL protein, humanVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID19657044
PMCPMC2730863
OpenAlexW1964068099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.