ArticleJournal of clinical microbiology2009
Molecular epidemiology of Brucella genotypes in patients at a major hospital in central Peru.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Molecular Investigation of the Transmission Pattern ofFrontiers in veterinary science · 2018Article
- Imported human brucellosis in Belgium: Bio and molecular typing of bacterial isolates, 1996-2015.PloS one · 2017Article
- MLVA Genotyping Characteristics of HumanFrontiers in microbiology · 2017Article
- A foodborne outbreak of brucellosis at a police station cafeteria, Lima, Peru.The American journal of tropical medicine and hygiene · 2013Article
- Infection of cattle in Kenya with Brucella abortus biovar 3 and Brucella melitensis biovar 1 genotypes.Tropical animal health and production · 2012Article
- Multiple-locus variable-number tandem-repeat analysis genotyping of human Brucella isolates from Turkey.Journal of clinical microbiology · 2011Article
- Antimicrobial susceptibility of Brucella melitensis isolates in Peru.Antimicrobial agents and chemotherapy · 2011Article
- Epidemiological and phylogenetic analysis of Spanish human Brucella melitensis strains by multiple-locus variable-number tandem-repeat typing, hypervariable octameric oligonucleotide fingerprinting, and rpoB typing.Journal of clinical microbiology · 2010Article
- Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens.PLoS neglected tropical diseases · 2010Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The multiple-locus variable-number repeat analysis of 90 human Brucella melitensis isolates from a large urban area in central Peru revealed variations at 4 (Bruce07, Bruce09, Bruce18, and Bruce42) out of 16 loci investigated, of which 1 (Bruce42) also is used for species identification. Ten genotypes were identified, separated by the number of Bruce42 repeats into two groups that may have distinct phenotypic characteristics. Whereas genotypes with five or six Bruce42 repeats were cultured mainly from adult patients, genotypes with three Bruce42 repeats were isolated from children and young adolescents as well as from adults. In addition, the isolates with three Bruce42 repeats were obtained more often from patients with splenomegaly (P = 0.02) or hepatomegaly (P = 0.006). An annual variation in the diversity of genotypes was observed, possibly reflecting changes in sources of fresh dairy products, supply routes to city shops and markets, and the movement of infected dairy goat herds.
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