Evidence map›Paper›PMID 19654018›Full record

ReviewMolecular aspects of medicine2009

Bacillus anthracis physiology and genetics.

Theresa M Koehler

Abstract readReview
In one paragraph

Review in Molecular aspects of medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 157 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Human anthrax vaccines: Current status and future prospects.Human vaccines & immunotherapeutics · 2025
    Review
  6. Article
  7. Article
  8. Spatiotemporal dynamics ofFrontiers in microbiology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Production of aLife (Basel, Switzerland) · 2022
    Article
  17. The transcription activator AtxA fromSynthetic biology (Oxford, England) · 2022
    Article
  18. Journal of bacteriology · 2021
    Article
  19. Article
  20. Toxins · 2020
    Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Theresa M KoehlerDepartment of Microbiology and Molecular Genetics, The University of Texas, Houston Health Science Center, Houston, TX, United States. Theresa.M.Koehler@uth.tmc.edu
The University of Texas Health Science Center at Houston · US

Funding

VIRULENCE GENE EXPRESSION BY BACILLUS ANTHRACISR01AI033537 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOEHLER, THERESA M. · 1998 to 2020
$5.4M
CONTROL OF PROTECTIVE ANTIGEN SYNTHESIS BY B ANTHRACISR29AI033537 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOEHLER, THERESA M. · 1993 to 1997
–
NIAID NIH HHS AI33537NIAID NIH HHS R01 AI033537
6 · The paper itself

Abstract

Bacillus anthracis is a member of the Bacillus cereus group species (also known as the "group 1 bacilli"), a collection of Gram-positive spore-forming soil bacteria that are non-fastidious facultative anaerobes with very similar growth characteristics and natural genetic exchange systems. Despite their close physiology and genetics, the B. cereus group species exhibit certain species-specific phenotypes, some of which are related to pathogenicity. B. anthracis is the etiologic agent of anthrax. Vegetative cells of B. anthracis produce anthrax toxin proteins and a poly-d-glutamic acid capsule during infection of mammalian hosts and when cultured in conditions considered to mimic the host environment. The genes associated with toxin and capsule synthesis are located on the B. anthracis plasmids, pXO1 and pXO2, respectively. Although plasmid content is considered a defining feature of the species, pXO1- and pXO2-like plasmids have been identified in strains that more closely resemble other members of the B. cereus group. The developmental nature of B. anthracis and its pathogenic (mammalian host) and environmental (soil) lifestyles of make it an interesting model for study of niche-specific bacterial gene expression and physiology.

Indexed as

AnimalsAnthraxAntigens, BacterialBacillus anthracisBacterial CapsulesBacterial ProteinsBacterial ToxinsBacteriophagesConjugation, GeneticEnvironmentGene Expression Regulation, BacterialGenome, BacterialPhenotypePlasmidsSoil Microbiologyanthrax toxinAntigens, BacterialBacterial ProteinsBacterial Toxins

Identifiers

PMID19654018
PMCPMC2784286
OpenAlexW1968670929

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.