Evidence map›Paper›PMID 19653944›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2009

Assessment of immune activation in mice before and after eradication of mite infestation.

Nancy A Johnston, Rita A Trammell, Susan Ball-Kell, Steven Verhulst, Linda A Toth

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Ivermectin-compounded Feed Compared with Topical Moxidectin-Imidacloprid for Eradication ofJournal of the American Association for Laboratory Animal Science : JAALAS · 2018
    Article
  5. Article
  6. Article
  7. Combined evaluation of commonly used techniques, including PCR, for diagnosis of mouse fur mites.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014
    Article
  8. Evaluation of diagnostic methods for Myocoptes musculinus according to age and treatment status of mice (Mus musculus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Article
  9. Soiled bedding sentinels for the detection of fur mites in mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2011
    Article
  10. Treatment and eradication of murine fur mites: III. Treatment of a large mouse colony with ivermectin-compounded feed.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010
    Article
  11. Treatment and eradication of murine fur mites: I. Toxicologic evaluation of ivermectin-compounded feed.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010
    Article
  12. The rodent quarantine quagmire.Journal of the American Association for Laboratory Animal Science : JAALAS · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nancy A JohnstonDepartment of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois; Division of Laboratory Animal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois. njohnston@siumed.edu
Rita A Trammell
Susan Ball-Kell
Steven Verhulst
Linda A Toth
Southern Illinois University School of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mite infestation of mice remains a persistent problem for many institutions, leading to numerous health problems and creating unknown and unwanted variables for research. In this study, mice with mite infestation demonstrated significantly higher levels of inflammatory cytokines, both at draining lymph nodes (axillary) and systemically, as compared with mice without mites. In addition, histologic evaluation revealed significant inflammation in mite-infested mice. Inflammatory changes were still present in the skin of mice at 6 to 8 wk after treatment, despite absence of detectable infestation at that time. Because these significant and lasting local and systemic changes have the potential to alter research findings, eradication of mites infestations should be an important goal for all institutions.

Indexed as

AnimalsChemokinesCytokinesFemaleHousing, AnimalImmune SystemInsecticidesLymph NodesMaleMiceMice, KnockoutMice, Mutant StrainsMice, TransgenicMite InfestationsMitesRodent DiseasesChemokinesCytokinesInsecticides

Identifiers

PMID19653944
PMCPMC2715926
OpenAlexW116685239

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.