ArticleAnnals of surgical oncology2009
Are mastectomies on the rise? A 13-year trend analysis of the selection of mastectomy versus breast conservation therapy in 5865 patients.
Article in Annals of surgical oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
116 citing papers in PubMed, 3 syntheses or guidelines pooled it, 326 citations in OpenAlex.
- Different types of implants for reconstructive breast surgery.The Cochrane database of systematic reviews · 2016Pooled it
- Pooled it
- The prognosis of breast cancer patients after mastectomy and immediate breast reconstruction: a meta-analysis.PloS one · 2015Pooled it
- Weekly taxane-anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer: a randomized controlled trial.Chinese journal of cancer · 2017Trial
- Trial
- Local control following single-dose intraoperative radiotherapy prior to surgical excision of early-stage breast cancer.Annals of surgical oncology · 2011Trial
- Article
- Rethinking Preoperative MRI in Early Breast Cancer: Who Truly Benefits?European journal of breast health · 2026Article
- ASO Author Reflections: Redefining Breast-Conserving Therapy: National Trends in Oncoplastic Reconstruction.Annals of surgical oncology · 2026Article
- Assessing Recent Trends in Lumpectomy and Concomitant Oncoplastic Procedures: A National Insurance Database Analysis.Annals of surgical oncology · 2026Article
- Quality of life in breast cancer survivors: a comparative analysis between breast conservative treatment (BCT) and post-mastectomy breast reconstruction (PMBR) using either autologous or prosthetic reconstruction.Updates in surgery · 2026Article
- Impact of breast cancer surgical procedures on postoperative daily life: a multicenter patient-reported outcomes study.International journal of clinical oncology · 2026Observational
- Assessment of Surgical Approach and Overall Survival in Young Women With Breast Cancer.European journal of breast health · 2026Article
- Postoperative Outcomes of Single-Port Robot-Assisted Versus Conventional Nipple-Sparing Mastectomy with Immediate Reconstruction.Annals of surgical oncology · 2026Article
- Retrospective study of hospitalized breast cancer patients in a Zhuhai-based hospital: analysis spanning over 20 years.Frontiers in oncology · 2026Article
- Comparing Survival Differences between Patients Undergoing Breast-Conserving Therapy Versus Total Mastectomy as a First Treatment for Early Stage Breast Cancer.Annals of surgical oncology · 2025Article
- Real-World Application of Alliance ACOSOG Z11102: How Many Patients Can be Spared Mastectomy?Annals of surgical oncology · 2025Article
- Review
- Complications of Prosthetic Breast Reconstruction in Prophylactic Versus Therapeutic Mastectomy: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Recurrence Patterns and Long-Term Results After Curative Surgery for Patients With Breast Cancer.Annals of surgical oncology · 2025Article
56 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe equivalency of survival between mastectomy and breast conservation therapy (BCT) has long been established, resulting in two decades of predominant BCT. Recently, surgeons have recognized a trend toward increasing mastectomy. Institutional trends of mastectomy and BCT were reviewed, confirming this perception in the surgical treatment of breast cancer. This report evaluates the factors that influence patient decisions to choose surgical therapies.
methodsPatients who underwent mastectomy or BCT for invasive and in situ breast cancer were identified upon retrospective review of a prospectively accrued breast cancer database between 1994 and 2007. Univariate and multivariate logistic regression analysis were used to estimate the odds ratio (OR) of the association between mastectomy and patients' clinicopathologic characteristics.
resultsOf the 5,865 patients, 3,736 underwent BCT and 2,129 underwent mastectomy. The overall surgical volume decreased during the study period. Mastectomy rates during the periods of 1994-1998, 1999-2003, and 2004-2007 were 33%, 33%, and 44%, respectively (P < 0.01). Immediate reconstruction rates decreased during the same time periods from 16%, 5%, and 7%, respectively (P < 0.01). On logistic regression analysis, gender, age < 40 years, increase tumor size, and lymphovascular invasion were significant independent predictors of mastectomy. The mastectomy rate increased during the period 1999-2003 (OR 1.2) and during 2004-2007(OR 1.8).
conclusionsThe perception of an increasing choice toward mastectomy has been confirmed at this institution. Possible reasons are younger population with higher lifetime risk, higher stage disease, and more biologically aggressive or diffuse tumors. Patient preference, fear of genetic or recurrence risk, and "intangible" factors seem to shift decisions toward mastectomy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.