Evidence map›Paper›PMID 19653000›Full record

ReviewMedical microbiology and immunology2009

The clinical value of neutrophil extracellular traps.

Tim Lögters, Stefan Margraf, Jens Altrichter, Jindrich Cinatl, Steffen Mitzner, Joachim Windolf, Martin Scholz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical microbiology and immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 113 citations in OpenAlex.

  1. Animals : an open access journal from MDPI · 2025
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  14. Resolvin D2 Limits Secondary Tissue Necrosis After Burn Wounds in Rats.Journal of burn care & research : official publication of the American Burn Association · 2018
    Article
  15. The systemic immune response to pediatric thermal injury.International journal of burns and trauma · 2018
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tim LögtersDepartment of Trauma and Hand Surgery, Heinrich-Heine University, Düsseldorf, Germany.
Stefan Margraf
Jens Altrichter
Jindrich Cinatl
Steffen Mitzner
Joachim Windolf
Martin Scholz
Heinrich Heine University Düsseldorf · DEGoethe University Frankfurt · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) have recently been discovered as a central part of antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also generated upon non-infectious stimuli in various clinical settings. In acute or chronic inflammatory disorders aberrantly enhanced NET formation and/or decreased NET degradation seems to correlate with disease outcome. This review summarizes current knowledge about the relation of NETs in a broad spectrum of clinical settings. Specifically, we focus on the importance of NETs as a predictive marker in severely ill patients and further, we speculate about the potential pathophysiology of NETs.

Indexed as

Autoimmune DiseasesBlood PlateletsExtracellular SpaceHumansImmunity, InnateNeutrophil ActivationNeutrophils

Identifiers

PMID19653000
OpenAlexW2076659259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.