Evidence map›Paper›PMID 19652918›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2009

The implications of fetal programming of glomerular number and renal function.

Jörg Dötsch, Christian Plank, Kerstin Amann, Julie Ingelfinger

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Impact of fetal programming, birth weight, and infant feeding on later hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2012
    Review
  12. Fetal programming of renal function.Pediatric nephrology (Berlin, Germany) · 2012
    Review
  13. Article
  14. Hypersensitivity to acute ANG II in female growth-restricted offspring is exacerbated by ovariectomy.American journal of physiology. Regulatory, integrative and comparative physiology · 2011
    Article
  15. Article
  16. Review
  17. Frontiers in the pathogenesis of kidney disease.Journal of molecular medicine (Berlin, Germany) · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jörg DötschDepartment of Pediatric Nephrology, University of Erlangen-Nuremberg, Loschgestrasse 15, 91054, Erlangen, Germany. Joerg.Doetsch@uk-erlangen.de
Christian Plank
Kerstin Amann
Julie Ingelfinger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large epidemiological studies suggest a clear relation between low birth weight and adverse renal outcomes evident as early as during childhood. Such adverse outcomes may include glomerular disease, hypertension, and renal failure. Data from autopsy material and from experimental models suggest that reduction in nephron number via diminished nephrogenesis may be a major mechanism, and factors that lead to this reduction are incompletely elucidated. Other mechanisms appear to be renal (e.g., via the intrarenal renin-angiotensin-aldosterone system) and nonrenal (e.g. changes in endothelial function). It also appears likely that the outcomes of fetal programming may be influenced postnatally, for example, by the amount of nutrients given at critical times.

Indexed as

Fetal DevelopmentKidney GlomerulusHumansInfant, Low Birth WeightInfant, NewbornKidney

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.