ArticleMolecular biology reports2010
Confirmed association between a single nucleotide polymorphism in the FTO gene and obesity-related traits in heavy pigs.
Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 53 citations in OpenAlex.
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- Single-nucleotide polymorphism detecting of some candidate genes related to lipid metabolism in Booroola Merino-Afshari sheep by Bayesian model averaging.Tropical animal health and production · 2021Article
- Genetic Variants in STAT3 Promoter Regions and Their Application in Molecular Breeding for Body Size Traits in Qinchuan Cattle.International journal of molecular sciences · 2018Article
- Reduced Representation Libraries from DNA Pools Analysed with Next Generation Semiconductor Based-Sequencing to Identify SNPs in Extreme and Divergent Pigs for Back Fat Thickness.International journal of genomics · 2015Article
- Novel SNP in the coding region of the FTO gene is associated with marbling score in Hanwoo (Korean cattle).Journal of animal science and technology · 2014Article
- Molecular characterization and expression analysis of fat mass and obesity-associated gene in rabbit.Journal of genetics · 2013Article
- Effect of FTO Expression and Polymorphism on Fat Deposition in Suzhong Pigs.Asian-Australasian journal of animal sciences · 2013Article
- Effects of DGAT1 gene on meat and carcass fatness quality in Chinese commercial cattle.Molecular biology reports · 2013Article
- An integrated approach of comparative genomics and heritability analysis of pig and human on obesity trait: evidence for candidate genes on human chromosome 2.BMC genomics · 2012Article
- BRCA1: a new candidate gene for bovine mastitis and its association analysis between single nucleotide polymorphisms and milk somatic cell score.Molecular biology reports · 2012Article
- Association between polymorphism in the FTO gene and growth and carcass traits in pig crosses.Genetics, selection, evolution : GSE · 2012Article
- Association between polymorphisms in cathepsin and cystatin genes with meat production and carcass traits in Italian Duroc pigs: confirmation of the effects of a cathepsin L (CTSL) gene marker.Molecular biology reports · 2012Article
- Single nucleotide polymorphism of CACNA2D1 gene and its association with milk somatic cell score in cattle.Molecular biology reports · 2011Article
- Molecular cloning and characterization of the porcine FTO promoter and coding regions.Molecular biology reports · 2011Article
- The porcine TBC1D1 gene: mapping, SNP identification, and association study with meat, carcass and production traits in Italian heavy pigs.Molecular biology reports · 2011Article
- Novel SNPs of the bovine CACNA2D1 gene and their association with carcass and meat quality traits.Molecular biology reports · 2011Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We recently showed that a polymorphism in the fat mass and obesity associated (FTO) gene (AM931150: g.276T > G) is associated with fat deposition traits in pigs. To confirm this result, we genotyped this polymorphism in an Italian Duroc population made up by 313 performance tested pigs with known estimated breeding values (EBVs) for average daily gain, back fat thickness (BFT), feed:gain ratio, lean cuts (LC), and visible intermuscular fat (VIF, a measure of intermuscular fat in the hams). In addition, we genotyped 148 commercial heavy pigs for which several fat deposition traits and lean meat percentage were measured. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits (VIF, BFT and LC) in the Italian Duroc pigs (P < 0.01) and in the commercial pigs (intramuscular fat content of different muscles, P < 0.05 or P < 0.10; lean meat content, P < 0.05; BFT, P < 0.05; intermuscular fat content in the hams, P < 0.05).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.