Evidence map›Paper›PMID 19649680›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Ischemic patterns assessed by positron emission tomography predict adverse outcome in patients with idiopathic dilated cardiomyopathy.

Richard M de Jong, Rene A Tio, Pim van der Harst, Adriaan A Voors, Paul M Koning, Clark J A M Zeebregts, Dirk J van Veldhuisen, Rudi A J O Dierckx, Riemer H J A Slart

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Positron emission tomography: An additional prognostic tool in dilated cardiomyopathy?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  4. Abnormalities of myocardial perfusion and glucose metabolism in patients with isolated left ventricular non-compaction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  5. Observational
  6. Article
  7. Article
  8. Myocardial perfusion PET: a split function?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Richard M de JongThoraxcenter, Department of Cardiology, University Medical Centre Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. R.M.de.Jong@thorax.umcg.nl
Rene A Tio
Pim van der Harst
Adriaan A Voors
Paul M Koning
Clark J A M Zeebregts
Dirk J van Veldhuisen
Rudi A J O Dierckx
Riemer H J A Slart
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough patients with idiopathic dilated cardiomyopathy (DCM) have no coronary artery disease, regional impairment of myocardial perfusion combined with preserved metabolism has been found using positron emission tomography (PET). Our aim was to assess the prognostic relevance of PET-mismatch between stress myocardial perfusion and glucose uptake on clinical outcome in DCM.

methodsIn 24 patients with DCM who underwent both myocardial perfusion and metabolism PET scanning, "mismatch" was assessed and the association with clinical outcome (hospitalization, mortality, and heart transplantation) was investigated.

resultsMismatch was found in 16 patients (66.7%). Univariate analysis showed that the presence of mismatch was associated with adverse outcome (P = 0.03). After adjustment for sex and age, the association remained significant with an adjusted relative risk of 10.4 (95% CI 1.1-103; P = 0.04) for death, heart transplant, or hospitalization. Univariate analysis also showed that a higher extent of mismatch was significantly associated with adverse outcome (P = 0.02). After adjusting for sex and age, the association remained significant with an adjusted relative risk of 6.5 [95% CI 1.2-36; P = 0.03] for death, heart transplantation, or hospitalization.

conclusionPET stress perfusion-metabolism mismatch, indicative for ischemia, is frequently found in DCM patients and related to a poorer outcome.

Indexed as

Cardiomyopathy, DilatedComorbidityFemaleHumansMaleMiddle AgedMyocardial IschemiaNetherlandsPositron-Emission TomographyPrevalenceRisk AssessmentRisk FactorsSurvival AnalysisSurvival Rate

Identifiers

PMID19649680
PMCPMC2746307
OpenAlexW2104511584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.