Evidence map›Paper›PMID 19648392›Full record

ReviewMayo Clinic proceedings2009

Primary and secondary prevention of cardiovascular diseases: a practical evidence-based approach.

James H O'Keefe, Maia D Carter, Carl J Lavie

Open access · bronzeAbstract readReview
In one paragraph

Review in Mayo Clinic proceedings, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
  2. Yoga for secondary prevention of coronary heart disease.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Trial
  4. The Fremantle Primary Prevention Study: a multicentre randomised trial of absolute cardiovascular risk reduction.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
    Trial
  5. Trial
  6. Article
  7. Review
  8. Comorbidity and modifiable risk factors in multiple sclerosis.Therapeutic advances in neurological disorders · 2026
    Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Dietary Habits of Patients with Coronary Artery Disease: A Case-Control Study from Pakistan.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

James H O'KeefeMid America Heart Institute and University of Missouri-Kansas City, Missouri, USA. jhokeefe@cc-pc.com
Maia D Carter
Carl J Lavie
Missouri Heart Center · USOchsner Medical Center · USUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the fact that we possess highly effective tools for the primary and secondary prevention of myocardial infarction and other complications of atherosclerosis, coronary heart disease remains the most common cause of death in our society. Arterial inflammation and endothelial dysfunction play central roles in the pathogenesis of atherosclerosis and adverse cardiovascular (CV) events. Therapeutic lifestyle changes in conjunction with an aggressive multidrug regimen targeted toward the normalization of the major CV risk factors will neutralize the atherogenic milieu, reduce vascular inflammation, and markedly decrease the risk of adverse CV events and need for revascularization procedures. Specific CV risk factors and optimal therapies for primary and secondary prevention are discussed.

Indexed as

Evidence-Based MedicineAlcohol DrinkingCardiovascular DiseasesCoronary Artery DiseaseDietFatty Acids, Omega-3FemaleHumansHypertensionLife StyleMaleObesityPrimary PreventionPrognosisRisk AssessmentSecondary PreventionFatty Acids, Omega-3

Identifiers

PMID19648392
PMCPMC2719528
OpenAlexW2166561366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.