Evidence map›Paper›PMID 19647461›Full record

ArticleJournal of feline medicine and surgery2010

Effects of fluticasone propionate dosage in an experimental model of feline asthma.

Leah A Cohn, Amy E DeClue, Rachael L Cohen, Carol R Reinero

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 52 citations in OpenAlex.

  1. Time to face mask/spacer acceptance in dogs and cats.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
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  10. Comparison of pulmonary deposition of nebulizedJournal of veterinary internal medicine · 2021
    Article
  11. Treatment of naturally occurring asthma with inhaled fluticasone or oral prednisolone: A randomized pilot trial.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Leah A CohnUniversity of Missouri, College of Veterinary Medicine, Department of Veterinary Medicine and Surgery, Columbia, MO, USA. cohnl@missouri.edu
Amy E DeClue
Rachael L Cohen
Carol R Reinero
Missouri College · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cats with inflammatory bronchial disease are usually treated with glucocorticoid (GC) drugs to reduce airway inflammation. Inhalant GC delivery can preserve airway effects while systemic effects are minimized. An appropriate dosage regimen for inhaled GC in cats has not been investigated. A blinded, randomized, cross-over study design was used to investigate the ability of three different dosages of the inhalant GC fluticasone propionate delivered by metered dose inhaler to ameliorate eosinophilic airway inflammation in cats with experimentally induced allergic airway inflammation. Further, suppression of the hypothalamic-pituitary-adrenal axis (HPAA) at each dose was assessed. Fluticasone administered at dosages of 44, 110, or 220 microg q 12h reduced airway eosinophilia by 74%, 82%, or 81%, respectively (no difference). None of the dose regimens tested caused HPAA suppression. We conclude that a twice daily dosage of 44 microg fluticasone should be evaluated for the management of cats with naturally occurring inflammatory bronchial disease.

Indexed as

Administration, InhalationAndrostadienesAnimalsAnti-Asthmatic AgentsAsthmaBronchodilator AgentsCat DiseasesCatsDose-Response Relationship, DrugFemaleFluticasoneHypothalamo-Hypophyseal SystemMaleMetered Dose InhalersPituitary-Adrenal SystemRandom AllocationAndrostadienesAnti-Asthmatic AgentsBronchodilator AgentsFluticasone

Identifiers

PMID19647461
PMCPMC10911429
OpenAlexW2137210083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.