Evidence map›Paper›PMID 19646851›Full record

ReviewCurrent opinion in immunology2009

T cells in mycobacterial infection and disease.

Andrea M Cooper

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  7. Review
  8. Evolutionary Genetics ofMicroorganisms · 2021
    Review
  9. Tuberculosis vaccine development: from classic to clinical candidates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Review
  10. Review
  11. Urban Air Pollution Particulates Suppress Human T-Cell Responses toInternational journal of environmental research and public health · 2019
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Immunometabolism in Tuberculosis.Frontiers in immunology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Andrea M CooperThe Trudeau Institute, Inc., Saranac Lake, NY 12983, USA. acooper@trudeauinstitute.org

Funding

T cell memory to TB in the lungP01AI046530 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 1999 to 2013
$22.2M
T cell memory to TB in the lungR01AI069121 · NIAID · TRUDEAU INSTITUTE, INC. · PI COOPER, ANDREA M · 2008 to 2012
$2.3M
The role of IL-12p40 in the response of pulmonary dendritic cells to tuberculosisR01AI067723 · NIAID · TRUDEAU INSTITUTE, INC. · PI COOPER, ANDREA M · 2006 to 2010
$2.2M
NIAID NIH HHS AI046530NIAID NIH HHS AI067723NIAID NIH HHS AI069121NIAID NIH HHS P01 AI046530NIAID NIH HHS R01 AI067723NIAID NIH HHS R01 AI069121
6 · The paper itself

Abstract

There has been an increase in our understanding of the complexity of the T cell response to mycobacterial infection recently. Improved tools have allowed the determination of the location and kinetics of naïve T cell activation in the mouse as well the variety of function of mycobacteria-specific cells in humans. There is also an increased appreciation of the balance required during mycobacterial infection between anti-bacterial activity and control of the immunopathologic response. The integration of the T cell functional data with the consequences of infection should improve rational vaccine design.

Indexed as

AnimalsCytokinesHumansLungMiceMycobacterium tuberculosisPhagocytesT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTuberculosis, PulmonaryTuberculosis VaccinesVirulenceCytokinesTuberculosis Vaccines

Identifiers

PMID19646851
PMCPMC2746551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.