ArticleParasites & vectors2009
Transcriptome analysis of Taenia solium cysticerci using Open Reading Frame ESTs (ORESTES).
Article in Parasites & vectors, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Validation of reference genes for RT-qPCR relative expression analysis during cyst-to-early adult development of Taenia solium.PLoS neglected tropical diseases · 2026Article
- Transcriptome of Taenia solium during in vitro cyst activation and initial growth into the tapeworm stage.Scientific data · 2025Article
- Proteomic analysis ofFrontiers in veterinary science · 2022Article
- Taenia solium Cysticercosis and Its Impact in Neurological Disease.Clinical microbiology reviews · 2020Review
- A gel-free proteomic analysis of Taenia solium and Taenia crassiceps cysticerci vesicular extracts.Parasitology research · 2018Article
- A Role for Epitope Networking in Immunomodulation by Helminths.Frontiers in immunology · 2018Article
- Article
- Transcriptome sequencing and analysis of the zoonotic parasite Spirometra erinacei spargana (plerocercoids).Parasites & vectors · 2014Article
- Analysis of the expression of cytoskeletal proteins of Taenia crassiceps ORF strain cysticerci (Cestoda).Parasitology research · 2014Article
- STINGRAY: system for integrated genomic resources and analysis.BMC research notes · 2014Article
- Use of expressed sequence tags as an alternative approach for the identification of Taenia solium metacestode excretion/secretion proteins.BMC research notes · 2013Article
- Annotation of the transcriptome from Taenia pisiformis and its comparative analysis with three Taeniidae species.PloS one · 2012Article
- A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation.PLoS neglected tropical diseases · 2012Article
- Article
- Proteomic survey of the cestode Mesocestoides corti during the first 24 hours of strobilar development.Parasitology research · 2011Article
- Analyses of an expressed sequence tag library from Taenia solium, Cysticerca.PLoS neglected tropical diseases · 2010Article
- Proteomic study of activated Taenia solium oncospheres.Molecular and biochemical parasitology · 2010Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman infection by the pork tapeworm Taenia solium affects more than 50 million people worldwide, particularly in underdeveloped and developing countries. Cysticercosis which arises from larval encystation can be life threatening and difficult to treat. Here, we investigate for the first time the transcriptome of the clinically relevant cysticerci larval form.
resultsUsing Expressed Sequence Tags (ESTs) produced by the ORESTES method, a total of 1,520 high quality ESTs were generated from 20 ORESTES cDNA mini-libraries and its analysis revealed fragments of genes with promising applications including 51 ESTs matching antigens previously described in other species, as well as 113 sequences representing proteins with potential extracellular localization, with obvious applications for immune-diagnosis or vaccine development.
conclusionThe set of sequences described here will contribute to deciphering the expression profile of this important parasite and will be informative for the genome assembly and annotation, as well as for studies of intra- and inter-specific sequence variability. Genes of interest for developing new diagnostic and therapeutic tools are described and discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.