Evidence map›Paper›PMID 19645274›Full record

ReviewJournal of medical entomology2009

Ecology of Rickettsia felis: a review.

Kathryn E Reif, Kevin R Macaluso

Abstract readReview
In one paragraph

Review in Journal of medical entomology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed.

  1. Phylogenetic, genomic and morphological characterization ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
  2. Sympatric Occurrence ofMicroorganisms · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular Detection ofAnimals : an open access journal from MDPI · 2024
    Article
  13. Article
  14. Diagnosis of a RareCase reports in infectious diseases · 2024
    Article
  15. Dynamics of Infections in Cattle andPathogens (Basel, Switzerland) · 2023
    Article
  16. Feeding on aPathogens (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Current Data onMicroorganisms · 2022
    Article
  19. Molecular Detection of Rickettsia felis in Fleas of Companion Animals in East Texas.The American journal of tropical medicine and hygiene · 2022
    Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kathryn E ReifDepartment of Pathobiological Sciences, Louisiana State University, School of Veterinary Medicine, Skip Bertman Dr., Baton Rouge, LA 70803, USA.
Kevin R Macaluso

Funding

Role of fleas in transmission of rickettsiae: ecology of flea-borne spotted feverR21AI069248 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI MACALUSO, KEVIN R. · 2007 to 2009
$509k
Arthropod host-dependent influence on rickettsial pathogenicityR56AI104923 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI MACALUSO, KEVIN R. · 2013 to 2013
$345k
NIAID NIH HHS AI069248NIAID NIH HHS R21 AI069248NIAID NIH HHS R56 AI104923
6 · The paper itself

Abstract

It has been two decades since the first description of Rickettsia felis, and although a nearly cosmopolitan distribution is now apparent, much of the ecology of this unique microorganism remains unresolved. The cat flea, Ctenocephalides felis, is currently the only known biological vector of R. felis; however, molecular evidence of R. felis in other species of fleas as well as in ticks and mites suggests a variety of arthropod hosts. Studies examining the transmission of R. felis using colonized cat fleas have shown stable vertical transmission but not horizontal transmission. Likewise, serological and molecular tools have been used to detect R. felis in a number of vertebrate hosts, including humans, in the absence of a clear mechanism of horizontal transmission. Considered an emerging flea-borne rickettsiosis, clinical manifestation of R. felis infection in humans, including, fever, rash, and headache is similar to other rickettsial diseases. Recent advances toward further understanding the ecology of R. felis have been facilitated by stable R. felis-infected cat flea colonies, several primary flea isolates and sustained maintenance of R. felis in cell culture systems, and highly sensitive quantitative molecular assays. Here, we provide a synopsis of R. felis including the known distribution and arthropods infected; transmission mechanisms; current understanding of vertebrate infection and human disease; and the tools available to further examine R. felis.

Indexed as

AnimalsCatsHumansInsect VectorsMammalsRickettsia felisRickettsia InfectionsSiphonaptera

Identifiers

PMID19645274
PMCPMC12794530

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.