Evidence map›Paper›PMID 19644541›Full record

ArticleHead and neck pathology2009

Solitary fibrous tumor of the oral cavity: clinicopathologic and immunohistochemical study of 21 cases.

Esther M O'Regan, Vijay Vanguri, Carl M Allen, Lewis Roy Eversole, John M Wright, Sook-Bin Woo

Open access · bronzeAbstract read
In one paragraph

Article in Head and neck pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  10. Solitary fibrous tumor of the tongue.Autopsy & case reports · 2022
    Article
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  12. Review
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  17. Review
  18. Article
  19. The Spindle Cell Neoplasms of the Oral Cavity.Iranian journal of pathology · 2015
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Esther M O'ReganOral Maxillofacial Pathology, Dublin Dental School and Hospital, Dublin, Ireland. emoregan@gmail.com
Vijay Vanguri
Carl M Allen
Lewis Roy Eversole
John M Wright
Sook-Bin Woo
Brigham and Women's Hospital · USDublin Dental University Hospital · IETexas A&M University · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe clinical, morphologic, and immunohistochemical features of 21 cases of solitary fibrous tumor presenting in the oral cavity. There were 9 male and 12 female patients with a median age of 51 years (range 37-83). The most common locations included the buccal mucosa (the most common site), lip, maxillary or mandibular vestibule and tongue. Histopathologic examination showed well-circumscribed tumors with two well-defined patterns: the classic pattern with densely cellular areas alternating with hypocellular areas in a variably collagenous, vascular stroma and a more uniformly sclerotic pattern with only subtle classic areas. The spindle-shaped neoplastic cells consistently showed immunoreactivity for antibodies directed against CD34. Five of nineteen cases (26%) were reactive for CD99 and 19 of 19 for Bcl-2. Follow-up information was available in 17 cases and averaged 54 months, with no evidence of recurrence or metastasis in any of these patients. Awareness that solitary fibrous tumor may present in the oral cavity is important so that confusion with other spindle cell neoplasms can be avoided. We also briefly describe the differential diagnosis and compare this series, the largest single series of intraoral SFT, to cases previously reported in the literature.

Indexed as

AdultAgedAged, 80 and overAntigens, CD34Biomarkers, TumorFemaleHumansImmunohistochemistryMaleMiddle AgedMouth NeoplasmsProto-Oncogene Proteins c-bcl-2Solitary Fibrous TumorsAntigens, CD34Biomarkers, TumorProto-Oncogene Proteins c-bcl-2CD34Differential diagnosisOral cavitySolitary fibrous tumor

Identifiers

PMID19644541
PMCPMC2715455
OpenAlexW1979175116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.