ArticleProceedings of the Japan Academy. Series B, Physical and biological sciences2009
The Ay allele at the agouti locus reduces the size and alters the shape of the mandible in mice.
Article in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 8 citations in OpenAlex.
- Genetic analysis of the mandible morphology in DDD.Cg-Journal of genetics · 2019Article
- Effect of the Y chromosome on testis weight in mice.The Journal of veterinary medical science · 2015Article
- Further characterization of diabetes mellitus and body weight loss in males of the congenic mouse strain DDD.Cg-A(y.).The Journal of veterinary medical science · 2015Article
- Article
- Quantitative trait locus mapping of genes associated with vacuolation in the adrenal X-zone of the DDD/Sgn inbred mouse.BMC genetics · 2012Article
- Quantitative trait locus mapping of genes that control body length and plasma insulin-like growth factor 1 level in mice.BMC research notes · 2012Article
- Genetic dissection of testis weight in mice: quantitative trait locus analysis using F(2) intercrosses between strains with extreme testis weight, and association study using Y-consomic strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2011Article
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Abstract
To confirm my previous findings that the A(y) allele at the agouti locus reduced the mandible size and therefore altered the mandible shape in a KK mouse strain background, I further investigated the effects of the A(y) allele on mandible morphology on different strain backgrounds, DDD and B6. Principal component analysis revealed that the mandible was significantly smaller in A(y) mice (DDD-A(y) and B6-A(y)) than in corresponding non-A(y) mice (DDD and B6, respectively). Discriminant and canonical discriminant analyses revealed that most mice were classified correctly in their own strains, and misclassification was not observed between DDD (-A(y)) and B6 (-A(y)). The results confirmed that the A(y) allele reduced the mandible size and altered the mandible shape regardless of the strain background. However, the difference in mandible morphology between A(y) mice and the corresponding non-A(y) mice within a strain was not as large as that which intrinsically underlay the two strains. Possible mechanisms of the A(y) action are discussed.
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