ArticleMicrobiology (Reading, England)2009
Genealogical typing of Neisseria meningitidis.
Article in Microbiology (Reading, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- DiagnoDating: diagnostics for dated phylogenies in microbial population genetics.Molecular biology and evolution · 2026Article
- Multilocus sequence analysis reveals genetic diversity in Staphylococcus aureus isolate of goat with mastitis persistent after treatment with enrofloxacin.Scientific reports · 2021Article
- Establishment of the European meningococcal strain collection genome library (EMSC-GL) for the 2011 to 2012 epidemiological year.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- How clonal are Neisseria species? The epidemic clonality model revisited.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- ClonalFrameML: efficient inference of recombination in whole bacterial genomes.PLoS computational biology · 2015Article
- A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes.BMC genomics · 2014Article
- Characterization of pseudogenes in members of the order Frankineae.Journal of biosciences · 2013Article
- Description of an unusual Neisseria meningitidis isolate containing and expressing Neisseria gonorrhoeae-Specific 16S rRNA gene sequences.Journal of clinical microbiology · 2013Article
- Ribosomal proteins as biomarkers for bacterial identification by mass spectrometry in the clinical microbiology laboratory.Journal of microbiological methods · 2013Article
- Microevolutionary analysis of Clostridium difficile genomes to investigate transmission.Genome biology · 2012Article
- Microevolution of symbiotic Bradyrhizobium populations associated with soybeans in east North America.Ecology and evolution · 2012Article
- Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Resolution of a meningococcal disease outbreak from whole-genome sequence data with rapid Web-based analysis methods.Journal of clinical microbiology · 2012Article
- Evolutionary and genomic insights into meningococcal biology.Future microbiology · 2012Review
- Impact of homologous and non-homologous recombination in the genomic evolution of Escherichia coli.BMC genomics · 2012Article
- Ion torrent personal genome machine sequencing for genomic typing of Neisseria meningitidis for rapid determination of multiple layers of typing information.Journal of clinical microbiology · 2012Article
- The effect of iron availability on transcription of the Neisseria meningitidis fHbp gene varies among clonal complexes.Microbiology (Reading, England) · 2012Article
- Genotypic and phenotypic characterization of carriage and invasive disease isolates of Neisseria meningitidis in Finland.Journal of clinical microbiology · 2012Article
- Article
- Recombination and population structure in Salmonella enterica.PLoS genetics · 2011Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
Despite the increasing popularity of multilocus sequence typing (MLST), the most appropriate method for characterizing bacterial variation and facilitating epidemiological investigations remains a matter of debate. Here, we propose that different typing schemes should be compared on the basis of their power to infer clonal relationships and investigate the utility of sequence data for genealogical reconstruction by exploiting new statistical tools and data from 20 housekeeping loci for 93 isolates of the bacterial pathogen Neisseria meningitidis. Our analysis demonstrated that all but one of the hyperinvasive isolates established by multilocus enzyme electrophoresis and MLST were grouped into one of six genealogical lineages, each of which contained substantial variation. Due to the confounding effect of recombination, evolutionary relationships among these lineages remained unclear, even using 20 loci. Analyses of the seven loci in the standard MLST scheme using the same methods reproduced this classification, but were unable to support finer inferences concerning the relationships between the members within each complex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.