Evidence map›Paper›PMID 19643736›Full record

ReviewJournal of leukocyte biology2009

Innate immune control and regulation of influenza virus infections.

Jodi McGill, Jonathan W Heusel, Kevin L Legge

Open access · greenAbstract readReview
In one paragraph

Review in Journal of leukocyte biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 164 citations in OpenAlex.

  1. Trial
  2. Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012
    Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Strategies of Pathogens to Escape from NO-Based Host Defense.Antioxidants (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Association of KIR gene polymorphisms with COVID-19 disease.Clinical immunology (Orlando, Fla.) · 2022
    Article
  13. Article
  14. Article
  15. Nitric Oxide to Fight Viral Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  16. Antiviral potential of garlic (Trends in food science & technology · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Alveolar Macrophages Treated WithFrontiers in microbiology · 2019
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jodi McGillDepartment of Pathology and Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa 52242, USA.
Jonathan W Heusel
Kevin L Legge
University of Iowa · US

Funding

Role of Dendritic Cells in Immunity to Pulmonary Influenza Virus InfectionsR01AI071085 · NIAID · UNIVERSITY OF IOWA · PI LEGGE, KEVIN L · 2007 to 2011
$1.8M
Innate Immune Control of Influenza Virus InfectionR21AI076989 · NIAID · UNIVERSITY OF IOWA · PI HEUSEL, JONATHAN W, LEGGE, KEVIN L · 2007 to 2008
$402k
Role of Dendritic Cells in Immunity to Pulmonary Influenza Virus InfectionsR56AI071085 · NIAID · UNIVERSITY OF IOWA · PI LEGGE, KEVIN L · 2013 to 2013
$350k
NIAID NIH HHS AI071085NIAID NIH HHS AI076989NIAID NIH HHS R01 AI071085NIAID NIH HHS R21 AI076989NIAID NIH HHS R56 AI071085
6 · The paper itself

Abstract

Adaptive immune responses are critical for the control and clearance of influenza A virus (IAV) infection. However, in recent years, it has become increasingly apparent that innate immune cells, including natural killer cells, alveolar macrophages (aMphi), and dendritic cells (DC) are essential following IAV infection in the direct control of viral replication or in the induction and regulation of virus-specific adaptive immune responses. This review will discuss the role of these innate immune cells following IAV infection, with a particular focus on DC and their ability to induce and regulate the adaptive IAV-specific immune response.

Indexed as

Immunity, InnateAnimalsDendritic CellsHumansInfluenza A virusInfluenza, HumanKiller Cells, NaturalMacrophages, AlveolarVirus Replication

Identifiers

PMID19643736
PMCPMC2752015
OpenAlexW2151295474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.