Evidence map›Paper›PMID 19643174›Full record

ArticleHearing research2009

Different distributions of calbindin and calretinin immunostaining across the medial and dorsal divisions of the mouse medial geniculate body.

E Lu, D A Llano, S M Sherman

Abstract readComparative Study
In one paragraph

Article in Hearing research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Synaptic Properties of Layer 6 Auditory Corticothalamic Inputs in Normal Hearing and Noise-Induced Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  12. Excitatory cholecystokinin neurons of the midbrain integrate diverse temporal responses and drive auditory thalamic subdomains.Proceedings of the National Academy of Sciences of the United States of America · 2021
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  20. Adenosine AAnatomical record (Hoboken, N.J. : 2007) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

E LuDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
D A Llano
S M Sherman
University of Chicago · US

Funding

VISUAL DEPRIVATION OF THE VISUAL SYSTEMR01EY003038 · NEI · UNIVERSITY OF CHICAGO · PI SHERMAN, S. MURRAY · 1985 to 2007
$3.4M
Information processing in sensory systemsR01DC008794 · NIDCD · UNIVERSITY OF CHICAGO · PI SHERMAN, S. MURRAY · 2007 to 2016
$3.3M
Functional organization of auditory corticothalamic projection systemsK08DC008320 · NIDCD · UNIVERSITY OF CHICAGO · PI LLANO, DANIEL A · 2006 to 2007
$288k
NEI NIH HHS EY03038NEI NIH HHS R01 EY003038NIDCD NIH HHS DC008320NIDCD NIH HHS DC008794NIDCD NIH HHS K08 DC008320NIDCD NIH HHS R01 DC008794
6 · The paper itself

Abstract

We studied the distributions of calretinin and calbindin immunoreactivity in subdivisions of the mouse medial geniculate body and the adjacent paralaminar nuclei. We found that the vast majority of labeled cells in the dorsal division of the medial geniculate body were immunoreactive for calbindin-only, whereas most of the remaining labeled cells were double-labeled. Very few calretinin+ only cells were observed. By contrast, we observed significant proportions of calbindin+ only, calretinin+ only and double-labeled cells in the medial division of the medial geniculate body. Further, the distributions of calbindin-only, calretinin-only and double-labeled cells did not differ between the medial division of the medial geniculate body, the suprageniculate nucleus, the peripeduncular nucleus and the posterior intralaminar nucleus. We found essentially no somatic staining for either calbindin or calretinin in the ventral division of the medial geniculate body. These data suggest that there are distinct neurochemical differences between the two non-lemniscal auditory thalamic nuclei. In addition, these data extend previous observations that the medial division of the medial geniculate body shares many properties with the paralaminar group of nuclei.

Indexed as

Fluorescent Antibody Technique, IndirectAnimalsAuditory PathwaysCalbindin 2CalbindinsFemaleGeniculate BodiesImage Processing, Computer-AssistedMaleMiceMice, Inbred BALB CMicroscopy, FluorescenceS100 Calcium Binding Protein GThalamic NucleiCalb2 protein, mouseCalbindin 2CalbindinsS100 Calcium Binding Protein G

Identifiers

PMID19643174
PMCPMC2774761
OpenAlexW2038462312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.