ArticleThe Journal of nutrition2009
Newborn adiposity measured by plethysmography is not predicted by late gestation two-dimensional ultrasound measures of fetal growth.
Article in The Journal of nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Body Composition of Infants Born with Intrauterine Growth Restriction: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Antenatal dietary and lifestyle advice for women who are overweight or obese and the effect on fetal growth and adiposity: the LIMIT randomised trial.BJOG : an international journal of obstetrics and gynaecology · 2016Trial
- The relationship of newborn adiposity to fetal growth outcome based on birth weight or the modified neonatal growth assessment score.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2012Trial
- Neonatal birthweight prediction using two- and three-dimensional estimated fetal weight among borderline small fetuses.Journal of clinical ultrasound : JCU · 2025Article
- Newer Insights Into Fetal Growth and Body Composition.Frontiers in endocrinology · 2021Review
- Advances in assessing body composition during pregnancy.European journal of clinical nutrition · 2018Review
- Fetal growth pathology score: a novel ultrasound parameter for individualized assessment of third trimester growth abnormalities.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2018Article
- Air displacement plethysmography (pea pod) in full-term and pre-term infants: a comprehensive review of accuracy, reproducibility, and practical challenges.Maternal health, neonatology and perinatology · 2018Review
- Association of ultrasound-based measures of fetal body composition with newborn adiposity.Pediatric obesity · 2017Article
- Maternal Obesity and its Short- and Long-Term Maternal and Infantile Effects.Journal of clinical research in pediatric endocrinology · 2016Review
- Body composition during fetal development and infancy through the age of 5 years.European journal of clinical nutrition · 2015Review
- Infants born large-for-gestational-age display slower growth in early infancy, but no epigenetic changes at birth.Scientific reports · 2015Article
- Genetic risk score for prediction of newborn adiposity and large-for-gestational-age birth.The Journal of clinical endocrinology and metabolism · 2014Article
- Article
- A new formula for estimating fetal weight: The impression of biparietal diameter, abdominal circumference, mid-thigh soft tissue thickness and femoral length on birth weight.Iranian journal of reproductive medicine · 2013Article
- Prospective validation of fetal weight estimation using fractional limb volume.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Noninvasive measures of fetal and neonatal body composition may provide early identification of children at risk for obesity. Air displacement plethysmography provides a safe, precise measure of adiposity and has recently been validated in infants. Therefore, we explored relationships between term newborn percent body fat (%BF) measured by air displacement plethysmography to 2-dimensional ultrasound (2-D US) biometric measures of fetal growth and maternal and umbilical cord endocrine activity. A total of 47 mother/infant pairs were studied. Fetal biometrics by 2-D US and maternal blood samples were collected during late gestation (35 wk postmenstrual age); infants were measured within 72 h of birth. Fetal biometrics included biparietal diameter, femur length, head circumference, abdominal circumference (AC), and estimated fetal weight (EFW). Serum insulin, insulin-like growth factor (IGF) 1, IGF binding protein-3, and leptin concentrations were measured in umbilical cord and maternal serum. The mean %BF determined by plethysmography was 10.9 +/- 4.8%. EFW and fetal AC had the largest correlations with newborn %BF (R(2) = 0.14 and 0.10, respectively; P < 0.05); however, stepwise linear regression modeling did not identify any fetal biometric parameters as a significant predictor of newborn %BF. Newborn mid-thigh circumference (MTC; cm) and ponderal index (PI; weight, kg/length, cm(3)) explained 21.8 and 14.4% of the variability in %BF, respectively, and gave the best stepwise linear regression model (%BF = 0.446 MTC + 0.347 PI -29.692; P < 0.001). We conclude that fetal growth biometrics determined by 2-D US do not provide a reliable assessment of %BF in term infants.
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Registered trials
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