ArticleThe Plant cell2009
Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 83 citations in OpenAlex.
- Transverse cortical microtubule arrays form persistent unipolar domains in hypocotyl cells ofMolecular biology of the cell · 2025Article
- Development of a 45K pepper GBTS liquid-phase gene chip and its application in genome-wide association studies.Frontiers in plant science · 2024Article
- Anatomical observation and transcriptome analysis of branch-twisted mutations in Chinese jujube.BMC genomics · 2023Article
- Defects in division plane positioning in the root meristematic zone affect cell organization in the differentiation zone.Journal of cell science · 2022Article
- Study and QTL mapping of reproductive and morphological traits implicated in the autofertility of faba bean.BMC plant biology · 2022Article
- Cell twisting during desiccation reveals axial asymmetry in wall organization.Biophysical journal · 2022Article
- Characterization of a Novel Creeping Tartary Buckwheat (Frontiers in plant science · 2022Article
- Three-dimensional quantification of twisting in the Arabidopsis petiole.Journal of plant research · 2021Article
- Cellular requirements for PIN polar cargo clustering in Arabidopsis thaliana.The New phytologist · 2021Article
- Division of Labor Between Two Actin Nucleators-the Formin FH1 and the ARP2/3 Complex-inFrontiers in plant science · 2020Article
- Arabidopsis IPGA1 is a microtubule-associated protein essential for cell expansion during petal morphogenesis.Journal of experimental botany · 2019Article
- Phenotypic and genetic characterization of tomato mutants provides new insights into leaf development and its relationship to agronomic traits.BMC plant biology · 2019Article
- Arabidopsis petiole torsions induced by lateral light or externally supplied auxin require microtubule-associated TORTIFOLIA1/SPIRAL2.Protoplasma · 2018Article
- Convergent Evolution and the Diverse Ontogenetic Origins of Tendrils in Angiosperms.Frontiers in plant science · 2018Review
- Division Plane Orientation Defects Revealed by a Synthetic Double Mutant Phenotype.Plant physiology · 2018Article
- Expression and functional analyses of a Kinesin gene GhKIS13A1 from cotton (Gossypium hirsutum) fiber.BMC biotechnology · 2017Article
- The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing, root growth and response to abiotic and biotic stresses.PLoS genetics · 2017Article
- TNO1, a TGN-localized SNARE-interacting protein, modulates root skewing in Arabidopsis thaliana.BMC plant biology · 2017Article
- Protein Phosphatase 2Cs andThe Plant cell · 2017Article
- What determines direction of asymmetry: genes, environment or chance?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Several factors regulate plant organ growth polarity. tortifolia2 (tor2), a right-handed helical growth mutant, has a conservative replacement of Arg-2 with Lys in the alpha-tubulin 4 protein. Based on a published high-resolution (2.89 A) tubulin structure, we predict that Arg-2 of alpha-tubulin forms hydrogen bonds with the GTPase domain of beta-tubulin, and structural modeling suggests that these contacts are interrupted in tor2. Consistent with this, we found that microtubule dynamicity is reduced in the tor2 background. We investigated the developmental origin of the helical growth phenotype using tor2. One hypothesis predicts that cell division patterns cause helical organ growth in Arabidopsis thaliana mutants. However, cell division patterns of tor2 root tips appear normal. Experimental uncoupling of cell division and expansion suggests that helical organ growth is based on cell elongation defects only. Another hypothesis is that twisting is due to inequalities in expansion of epidermal and cortical tissues. However, freely growing leaf trichomes of tor2 mutants show right-handed twisting and cortical microtubules form left-handed helices as early as the unbranched stage of trichome development. Trichome twisting is inverted in double mutants with tor3, a left-handed mutant. Single tor2 suspension cells also exhibit handed twisting. Thus, twisting of tor2 mutant organs appears to be a higher-order expression of the helical expansion of individual cells.
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