ArticleThe Plant cell2009
Arabidopsis DUO POLLEN3 is a key regulator of male germline development and embryogenesis.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- Scalable eQTL mapping using single-nucleus RNA-sequencing of recombined gametes from a small number of individuals.PLoS biology · 2025Article
- DUO1 Activated Zinc Finger (AtDAZ) protein role in the generative cell body morphogenesis.Plant molecular biology · 2025Article
- Article
- The male germ unit association is independently regulated of GUM inPlant direct · 2024Article
- Cytological and transcriptomic analyses provide insights into the pollen fertility of synthetic allodiploid Brassica juncea hybrids.Plant cell reports · 2023Article
- Genetic control of generative cell shape by DUO1 in Arabidopsis.Plant reproduction · 2023Article
- Cell-type-specific alternative splicing in the Arabidopsis germline.Plant physiology · 2023Article
- Cycling in a crowd: Coordination of plant cell division, growth, and cell fate.The Plant cell · 2022Review
- Unravelling the Role of Epigenetic Modifications in Development and Reproduction of Angiosperms: A Critical Appraisal.Frontiers in genetics · 2022Review
- A Plastid-Bound Ankyrin Repeat Protein Controls Gametophyte and Early Embryo Development inFrontiers in plant science · 2022Article
- The transcriptional regulator GON4L is required for viability and hematopoiesis in mice.Experimental hematology · 2021Article
- Proteomic Analysis of Generative and Vegetative Nuclei Reveals Molecular Characteristics of Pollen Cell Differentiation inFrontiers in plant science · 2021Article
- Fertilization-Defective Gametophytic Mutant Screening: A Novel Approach.Frontiers in plant science · 2020Review
- Molecular Mechanisms of the Floral Biology ofFrontiers in plant science · 2020Review
- Studies on genome size estimation, chromosome number, gametophyte development and plant morphology of salt-tolerant halophyte Suaeda salsa.BMC plant biology · 2019Article
- Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes.Nature communications · 2018Article
- Pollen differentiation as well as pollen tube guidance and discharge are independent of the presence of gametes.Development (Cambridge, England) · 2018Article
- WRKY2/34-VQ20 Modules inFrontiers in plant science · 2018Article
- Anther-preferential expressing gene PMR is essential for the mitosis of pollen development in rice.Plant cell reports · 2017Article
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Abstract
Male germline development in angiosperms produces the pair of sperm cells required for double fertilization. A key regulator of this process in Arabidopsis thaliana is the male germline-specific transcription factor DUO POLLEN1 (DUO1) that coordinates germ cell division and gamete specification. Here, we uncover the role of DUO3, a nuclear protein that has a distinct, but overlapping role with DUO1 in male germline development. DUO3 is a conserved protein in land plants and is related to GON-4, a cell lineage regulator of gonadogenesis in Caenorhabditis elegans. Mutant duo3-1 germ cells either fail to divide or show a delay in division, and we show that, unlike DUO1, DUO3 promotes entry into mitosis independent of the G2/M regulator CYCB1;1. We also show that DUO3 is required for the expression of a subset of germline genes under DUO1 control and that like DUO1, DUO3 is essential for sperm cell specification and fertilization. Furthermore, we demonstrate an essential sporophytic role for DUO3 in cell division and embryo patterning. Our findings demonstrate essential developmental roles for DUO3 in cell cycle progression and cell specification in both gametophytic and sporophytic tissues.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.