Trial reportArchives of sexual behavior2010
Covert use, vaginal lubrication, and sexual pleasure: a qualitative study of urban U.S. Women in a vaginal microbicide clinical trial.
Trial report in Archives of sexual behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Variations in microbicide gel acceptability among young women in the USA and Puerto Rico.Culture, health & sexuality · 2012Trial
- Article
- The Role of Volume in the Perceptibility of Topical Vaginal Formulations: User Sensory Perceptions and Experiences of Heterosexual Couples During Vaginal Sex.AIDS research and human retroviruses · 2020Article
- Development of multipurpose technologies products for pregnancy and STI prevention: update on polyphenylene carboxymethylene MPT gel development†.Biology of reproduction · 2020Article
- Oral and vaginal HIV pre-exposure prophylaxis product attribute preferences among female sex workers in the Mexico-US border region.International journal of STD & AIDS · 2019Article
- Qualitative exploration of intrinsic and extrinsic factors that influence acceptability of semisoft vaginal suppositories.BMC women's health · 2018Article
- Achieving the optimal vaginal state: using vaginal products and study gels in Uganda, Zimbabwe, and South Africa.International journal of sexual health : official journal of the World Association for Sexual Health · 2017Article
- Innovative sensory methods to access acceptability of mixed polymer semisoft ovules for microbicide applications.Drug delivery and translational research · 2016Article
- The Potential of Pre-Exposure Prophylaxis for Women in Violent Relationships.AIDS patient care and STDs · 2016Review
- Drivers of Vaginal Drug Delivery System Acceptability from Internet-Based Conjoint Analysis.PloS one · 2016Article
- Hypothetical Rectal Microbicide Acceptability and Factors Influencing It among Men Who Have Sex with Men in Tianjin, China.PloS one · 2016Article
- Communication About Microbicide Use Between Couples in KwaZulu-Natal, South Africa.AIDS and behavior · 2015Article
- Optimizing HIV prevention for women: a review of evidence from microbicide studies and considerations for gender-sensitive microbicide introduction.Journal of the International AIDS Society · 2015Review
- Perspectives on HIV prevention among urban black women: a potential role for HIV pre-exposure prophylaxis.AIDS patient care and STDs · 2014Article
- Engaging male partners in women's microbicide use: evidence from clinical trials and implications for future research and microbicide introduction.Journal of the International AIDS Society · 2014Article
- Article
- Providing for women's pleasure in the next generation of condoms.The journal of sexual medicine · 2013Article
- Microbicide clinical trial adherence: insights for introduction.Journal of the International AIDS Society · 2013Review
- An assessment of the likely acceptability of vaginal microbicides for HIV prevention among women in rural Ghana.BMC women's health · 2012Article
- Moving beyond safe sex to women-controlled safe sex: a concept analysis.Journal of advanced nursing · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Using data from a U.S. clinical safety trial of tenofovir gel, a candidate microbicide, we explored the intersection of sexual pleasure and vaginal lubrication to understand whether and under what circumstances women would use a microbicide gel covertly with primary partners. This study question emerged from acceptability research in diverse settings showing that even though future microbicides are extolled as a disease prevention method that women could use without disclosing to their partners, many women assert they would inform their primary partner. Participants (N = 84), stratified by HIV-status and sexual activity (active vs. abstinent), applied the gel intra-vaginally for 14 days. At completion, quantitative acceptability data were obtained via questionnaire (N = 79) and qualitative data via small group discussions (N = 15 groups, 40 women). Quantitatively, 71% preferred a microbicide that could not be noticed by a sex partner and 86% experienced greater vaginal lubrication with daily use. Based on our analysis of the qualitative data, we suggest that women's perception that their primary partners would notice a microbicide gel is a more important reason for their caution regarding covert use than may previously have been recognized. Our findings also showed that women's assessment of the possibility of discreet, if not covert, use was strongly related to their perception of how a microbicide's added vaginal lubrication would influence their own and their partner's pleasure, as well as their partner's experience of his sexual performance. A microbicide that increases pleasure for both partners could potentially be used without engendering opposition from primary partners.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.