ArticlePloS one2009
Deciphering proteomic signatures of early diapause in Nasonia.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 78 citations in OpenAlex.
- A Head-Specific Transcriptomic Study Reveals Key Regulatory Pathways for Winter Diapause in the Mosquito Culex pipiens.Archives of insect biochemistry and physiology · 2025Article
- Endocrine and enzymatic shifts during insect diapause: a review of regulatory mechanisms.Frontiers in physiology · 2025Review
- Prolonged Heat Stress during Winter Diapause Alters the Expression of Stress-Response Genes inInternational journal of molecular sciences · 2024Article
- Suppression of the gene encoding PDZ domain-containing protein decreases cold tolerance and overwintering survival of the mosquito, Culex pipiens (Culicidae: Diptera).Journal of medical entomology · 2023Article
- Characterization and Developmental Expression Patterns of Four Hexamerin Genes in the Bumble Bee, Bombus terrestris (Hymenoptera: Apidae).Journal of insect science (Online) · 2021Article
- When your host shuts down: larval diapause impacts host-microbiome interactions in Nasonia vitripennis.Microbiome · 2021Article
- Embryonic developmental arrest in the annual killifish Austrolebias charrua: A proteomic approach to diapause III.PloS one · 2021Article
- Comparative proteomics provides insights into diapause program of Bactrocera minax (Diptera: Tephritidae).PloS one · 2020Article
- Understanding the regulation of overwintering diapause molecular mechanisms in Culex pipiens pallens through comparative proteomics.Scientific reports · 2019Article
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- Global Transcriptome Sequencing Reveals Molecular Profiles of Summer Diapause Induction Stage of Onion Maggot,G3 (Bethesda, Md.) · 2018Article
- Dormancy in Embryos: Insight from Hydrated Encysted Embryos of an Aquatic Invertebrate.Molecular & cellular proteomics : MCP · 2017Article
- Maternal and nourishment factors interact to influence offspring developmental trajectories in social wasps.Proceedings. Biological sciences · 2017Article
- Seasonal gene expression kinetics between diapause phases in Drosophila virilis group species and overwintering differences between diapausing and non-diapausing females.Scientific reports · 2015Article
- Development of a Nasonia vitripennis outbred laboratory population for genetic analysis.Molecular ecology resources · 2014Article
- Diapause, signal and molecular characteristics of overwintering Chilo suppressalis (Insecta: Lepidoptera: Pyralidae).Scientific reports · 2013Article
- Proteomic and metabolomic profiles of larval hemolymph associated with diapause in the cotton bollworm, Helicoverpa armigera.BMC genomics · 2013Article
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- Article
- Identification of gene expression changes associated with the initiation of diapause in the brain of the cotton bollworm, Helicoverpa armigera.BMC genomics · 2011Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Insect diapause is an alternative life-history strategy used to increase longevity and survival in harsh environmental conditions. Even though some aspects of diapause are well investigated, broader scale studies that elucidate the global metabolic adjustments required for this remarkable trait, are rare. In order to better understand the metabolic changes during early insect diapause, we used a shotgun proteomics approach on early diapausing and non-diapausing larvae of the recently sequenced hymenopteran model organism Nasonia vitripennis. Our results deliver insights into the molecular underpinnings of diapause in Nasonia and corroborate previously reported diapause-associated features for invertebrates, such as a diapause-dependent abundance change for heat shock and storage proteins. Furthermore, we observed a diapause-dependent switch in enzymes involved in glycerol synthesis and a vastly changed capacity for protein synthesis and degradation. The abundance of structural proteins and proteins involved in protein synthesis decreased with increasing diapause duration, while the abundance of proteins likely involved in diapause maintenance (e.g. ferritins) increased. Only few potentially diapause-specific proteins were identified suggesting that diapause in Nasonia relies to a large extent on a modulation of pre-existing pathways. Studying a diapause syndrome on a proteomic level rather than isolated pathways or physiological networks, has proven to be an efficient and successful avenue to understand molecular mechanisms involved in diapause.
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