ReviewTrends in neurosciences2009
Neocortical neurogenesis: morphogenetic gradients and beyond.
Review in Trends in neurosciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 81 citations in OpenAlex.
- Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators ofScience advances · 2025Article
- The Control of Cortical Folding: Multiple Mechanisms, Multiple Models.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- β-PIX-d, a Member of the ARHGEF7 Guanine Nucleotide Exchange Factor Family, Activates Rac1 and Induces Neuritogenesis in Primary Cortical Neurons.Experimental neurobiology · 2024Article
- Out of Line or Altered States? Neural Progenitors as a Target in a Polygenic Neurodevelopmental Disorder.Developmental neuroscience · 2024Review
- Microglial Characterization in Transient Human Neurodevelopmental Structures.Developmental neuroscience · 2023Article
- Systematic modelling of the development of laminar projection origins in the cerebral cortex: Interactions of spatio-temporal patterns of neurogenesis and cellular heterogeneity.PLoS computational biology · 2020Article
- High Angular Resolution Diffusion MRI Reveals Conserved and Deviant Programs in the Paths that Guide Human Cortical Circuitry.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Wnt/β-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind.FEBS letters · 2019Review
- Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Coordination of Neuron Production in Mouse and Human Cerebral Cortex by the Homolog of Drosophila Mastermind Protein.Brain, behavior and evolution · 2019Article
- Comprehensive computational modelling of the development of mammalian cortical connectivity underlying an architectonic type principle.PLoS computational biology · 2018Article
- Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.Cellular and molecular life sciences : CMLS · 2018Article
- Serum-mediated Activation of Bone Marrow-derived Mesenchymal Stem Cells in Ischemic Stroke Patients: A Novel Preconditioning Method.Cell transplantation · 2018Article
- Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects inFrontiers in molecular neuroscience · 2018Article
- Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity.Frontiers in cellular neuroscience · 2017Review
- Evolution of cytoarchitectural landscapes in the mammalian isocortex: Sirenians (Trichechus manatus) in comparison with other mammals.The Journal of comparative neurology · 2016Article
- Article
- Morphogenetic and Histogenetic Roles of the Temporal-Spatial Organization of Cell Proliferation in the Vertebrate Corticogenesis as Revealed by Inter-specific Analyses of the Optic Tectum Cortex Development.Frontiers in cellular neuroscience · 2016Review
- Prenatal Neurogenesis in Autism Spectrum Disorders.Frontiers in chemistry · 2016Review
- Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis.The EMBO journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Each of the five cellular layers of the cerebral neocortex is composed of a specific number of a single predominant 'class' of projection neuron. The projection neuron class is defined by its unique morphology and axonal projections to other areas of the brain. Precursor cell populations lining the embryonic lateral ventricles produce the projection neurons. The mechanisms regulating precursor cell proliferation also regulate total numbers of neurons produced at specific developmental periods and destined to a specific neocortical layer. Because the newborn neurons migrate relatively long distances to reach their final layer destinations, it is often assumed that the mechanisms governing acquisition of neuronal-class-specific characteristics, many of which become evident after neuron production, are independent of the mechanisms governing neuron production. We review evidence that suggests that the two mechanisms might be linked via operations of Notch1 and p27(Kip1), molecules known to regulate precursor cell proliferation and neuron production.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.