Trial reportContemporary clinical trials2009
Design of the Value of Urodynamic Evaluation (ValUE) trial: A non-inferiority randomized trial of preoperative urodynamic investigations.
Trial report in Contemporary clinical trials, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00803959 (A Randomized Trial of Urodynamic Testing Before Stress-Incontinence Surgery), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Urodynamic Testing Before Stress-Incontinence Surgery
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Urodynamic studies for management of urinary incontinence in children and adults.The Cochrane database of systematic reviews · 2013Pooled it
- Vaginal Erbium Laser Versus Pelvic Floor Muscle Training for Stress Urinary Incontinence: A Randomised Controlled Trial.International urogynecology journal · 2025Trial
- Methods for a multicenter randomized trial for mixed urinary incontinence: rationale and patient-centeredness of the ESTEEM trial.International urogynecology journal · 2016Trial
- Pre-operative urodynamics in women with stress urinary incontinence increases physician confidence, but does not improve outcomes.Neurourology and urodynamics · 2014Trial
- Surgical preparation: are patients "ready" for stress urinary incontinence surgery?International urogynecology journal · 2014Trial
- The effect of urodynamic testing on clinical diagnosis, treatment plan and outcomes in women undergoing stress urinary incontinence surgery.The Journal of urology · 2013Trial
- A randomized trial of urodynamic testing before stress-incontinence surgery.The New England journal of medicine · 2012Trial
- Trial
- Geographic Access to Urodynamics Studies in the United States: A Medicare-Based Geospatial Analysis.Cureus · 2026Article
- The Efficacy of Modified Laparoscopic Burch Procedure Using a Single Stitch on Each Side of the Urethra for the Treatment of Stress Urinary Incontinence.Medicina (Kaunas, Lithuania) · 2025Article
- Factors associated with polyacrylamide hydrogel outcomes in women with stress urinary incontinence.BJUI compass · 2023Article
- Evaluation of the urinary microbiota of women with uncomplicated stress urinary incontinence.American journal of obstetrics and gynecology · 2017Article
- Predicting urinary incontinence after surgery for pelvic organ prolapse.Current opinion in obstetrics & gynecology · 2016Review
- Preoperative clinical, demographic, and urodynamic measures associated with failure to demonstrate urodynamic stress incontinence in women enrolled in two randomized clinical trials of surgery for stress urinary incontinence.International urogynecology journal · 2013Article
- When are urodynamics indicated in patients with stress urinary incontinence?Current urology reports · 2012Review
- What is an evidence-based appropriate workup?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2012Article
- Comparison of the cough stress test and 24-h pad test in the assessment of stress urinary incontinence.International urogynecology journal · 2012Article
- Novel biomarkers for overactive bladder.Nature reviews. Urology · 2011Review
- Are multichannel urodynamics required prior to surgery in a woman with stress urinary incontinence?Current urology reports · 2010Review
- Preoperative abdominal straining in uncomplicated stress urinary incontinence: is there a correlation with voiding dysfunction andTherapeutic advances in urologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 13 institutions in 1 country.
Funding
Abstract
background and purposeUrodynamic studies (UDS) are routinely obtained prior to surgery for stress urinary incontinence (SUI) despite a lack of evidence that UDS information has an actual impact on outcome. The primary aim of this non-inferiority randomized clinical trial is to determine whether women with symptomatic, uncomplicated SUI who undergo only a basic office evaluation (BOE) prior to SUI surgery (No UDS arm) have non-inferior treatment outcomes compared to women who have BOE and UDS (UDS arm). Secondary aims are: 1) to determine how often physicians use preoperative UDS results to alter clinical and surgical decision-making, 2) to compare the amount of improvement in incontinence outcomes, and 3) to determine the incremental cost and utility of performing UDS compared with not performing UDS.
methodsAfter an initial basic office evaluation, women planning surgery for uncomplicated SUI who consent to study participation will be randomized to receive preoperative UDS or No UDS. Treatment will be planned and performed by the surgeon utilizing all the data available to them. We will compare results from the basic office evaluation (No UDS) with results from the basic office evaluation and preoperative UDS.
resultsThe primary outcome will be measured at 12 months using responses to the Urogenital Distress Inventory and the Patient Global Index-Improvement.
conclusionsRandomized trials comparing the effects of different diagnostic alternatives on treatment outcomes pose study design challenges. A non-inferiority design is appropriate when comparing a less invasive and less expensive alternative with a standard of care approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.