ArticlePlanta2009
LeFRK2 is required for phloem and xylem differentiation and the transport of both sugar and water.
Article in Planta, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Mango Fructokinases Inhibit Sugar Accumulation and Enhance Energy Metabolism in Transgenic Tomato.Plants (Basel, Switzerland) · 2025Article
- Overexpression ofInternational journal of molecular sciences · 2024Article
- The AlkB Homolog SlALKBH10B Negatively Affects Drought and Salt Tolerance inInternational journal of molecular sciences · 2023Article
- Calcyclin-binding protein-promoted degradation of MdFRUCTOKINASE2 regulates sugar homeostasis in apple.Plant physiology · 2023Article
- A Comparative Characterization and Expression Profiling Analysis ofInternational journal of molecular sciences · 2022Article
- JULGI-mediated increment in phloem transport capacity relates to fruit yield in tomato.Plant biotechnology journal · 2022Article
- Sucrose Synthase and Fructokinase Are Required for Proper Meristematic and Vascular Development.Plants (Basel, Switzerland) · 2022Article
- A vacuolar hexose transport is required for xylem development in the inflorescence stem.Plant physiology · 2022Article
- Sugar and acid profile of loquat (Frontiers in plant science · 2022Article
- Transcriptomic Analysis Reveal the Molecular Mechanisms of Seed Coat Development inFrontiers in plant science · 2022Article
- What do we know about growth of vessel elements of secondary xylem in woody plants?Biological reviews of the Cambridge Philosophical Society · 2021Review
- MdFRK2-mediated sugar metabolism accelerates cellulose accumulation in apple and poplar.Biotechnology for biofuels · 2021Article
- Involvement of SUT1 and SUT2 Sugar Transporters in the Impairment of Sugar Transport and Changes in Phloem Exudate Contents in Phytoplasma-Infected Plants.International journal of molecular sciences · 2021Article
- Short De-Etiolation Increases the Rooting of VC801 Avocado Rootstock.Plants (Basel, Switzerland) · 2020Article
- Changes in the microsomal proteome of tomato fruit during ripening.Scientific reports · 2019Article
- Melatonin-Mediated Sugar Accumulation and Growth Inhibition in Apple Plants Involves Down-Regulation of Fructokinase 2 Expression and Activity.Frontiers in plant science · 2019Article
- MuMADS1 and MaOFP1 regulate fruit quality in a tomato ovate mutant.Plant biotechnology journal · 2018Article
- Increased activity of MdFRK2, a high-affinity fructokinase, leads to upregulation of sorbitol metabolism and downregulation of sucrose metabolism in apple leaves.Horticulture research · 2018Article
- Plant Fructokinases: Evolutionary, Developmental, and Metabolic Aspects in Sink Tissues.Frontiers in plant science · 2018Review
- Identification and biochemical characterization of the fructokinase gene family in Arabidopsis thaliana.BMC plant biology · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been suggested that LeFRK2, the major fructose-phosphorylating enzyme in tomato plants, may be required for stem xylem development. Yet, we do not know if this enzyme affects the development of individual vessels, whether it affects water conductance, or whether it affects phloem development and sugar transport. Here, we show that suppression of LeFRK2 results in a significant reduction in the size of vascular cells and slows fiber maturation. The vessels in stems of LeFRK2-antisense plants are narrower than in WT plants and have thinner secondary cell walls. Although the cambium produces rounded secondary vessels, these vessels become deformed during the early stages of xylem maturation. Water conductance is then reduced in stems, roots, and leaves, suggesting that LeFRK2 influences xylem development throughout the entire vascular system. Interestingly, the build-up of positive xylem pressure under static (no-flow) conditions was also decreased. Suppression of LeFRK2 reduced the length and width of the sieve elements, as well as callose deposition. To examine the effect of LeFRK2 suppression on phloem transport, we created triple-grafted plants in which a portion of the wild-type stem was replaced with an antisense interstcok, and compared the contents of the transported sugar, sucrose, in the different portions of these stems. Sucrose contents above and within the LeFRK2-antisense interstock were significantly higher than those below the graft. These results show that the antisense interstock restricted the downward movement of sucrose, suggesting that LeFRK2 is required for both phloem and xylem development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.