ArticleJournal of hypertension2009
Relation of blood pressure and body mass index during childhood to cardiovascular risk factor levels in young adults.
Article in Journal of hypertension, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Adolescent and Childhood Obesity and Excess Morbidity and Mortality in Young Adulthood-a Systematic Review.Current obesity reports · 2021Pooled it
- The Impact of Childhood and Adolescent Obesity on Cardiovascular Risk in Adulthood: a Systematic Review.Current diabetes reports · 2018Pooled it
- Cumulative childhood adversity and adult cardiometabolic disease: A meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018Pooled it
- Evaluation of an Electronic Clinical Decision Support Tool for Incident Elevated BP in Adolescents.Academic pediatricsTrial
- Longitudinal Insights Into Pediatric Hypertension, Cardiac Consequences, and Physical Activity.Current hypertension reports · 2026Review
- Associations between fibroblast growth factor 23 and cardiovascular disease in children and adolescents: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Article
- Socioeconomic status, prefrontal cortical volume, and cardiometabolic risk in early adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- Nutritional Status and Health Challenges Among Schoolchildren in Nepal's Solukhumbu Valley.Children (Basel, Switzerland) · 2025Article
- Arterial hypertension in infants with congenital diaphragmatic hernia following surgical repair.European journal of pediatrics · 2024Article
- Diagnosis and Treatment of Monogenic Hypertension in Children.Yonsei medical journal · 2023Review
- Determining independence and associations among various cardiovascular disease risk factors in 9-12 years old school-children: a cross sectional study.BMC public health · 2022Article
- Can adult polygenic scores improve prediction of body mass index in childhood?International journal of obesity (2005) · 2022Article
- Article
- The mediating pathways between parental separation in childhood and offspring hypertension at midlife.Scientific reports · 2022Article
- Assessing parents' self-efficacy to handle child obesity-related behaviors: validation of the Lifestyle Behavior Checklist in Iran.Journal of health, population, and nutrition · 2022Article
- Article
- The Early Life Course of Body Weight and Gene Expression Signatures for Disease.American journal of epidemiology · 2021Article
- Association of childhood anthropometric measurements and laboratory parameters with high blood pressure in young adults.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Childhood traffic-related air pollution and adverse changes in subclinical atherosclerosis measures from childhood to adulthood.Environmental health : a global access science source · 2021Article
- In utero exposure to gestational diabetes mellitus and cardiovascular risk factors in youth: A longitudinal analysis in the EPOCH cohort.Pediatric obesity · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
introductionAdult obesity and hypertension are leading causes of cardiovascular morbidity/mortality. Although childhood BMI and blood pressure (BP) track into adulthood, how they influence adult cardiovascular risk independent of each other is not well defined.
methodsParticipants were from two longitudinal studies with a baseline evaluation at mean age of 13 years and a follow-up at mean age of 24 years. Regression models using childhood BP and BMI to predict young adult cardiovascular risk factors were performed.
resultsIn univariate analysis, childhood BMI predicted young adult BP, lipids, glucose, insulin and insulin resistance, whereas childhood BP predicted young adult BP, lipids and glucose. In a multivariable regression model (adjusted for age, sex and race), which included change in BMI and BP from age 13 to 24 years, BMI predicted all young adult risk factors except BP and glucose. Baseline SBP predicted young adult BP, cholesterol, triglycerides and glucose whereas baseline DBP predicted young adult BP, BMI and glucose.
conclusionThe results from this study show that BP and BMI act independently in children to influence future cardiovascular risk factors and the combination of high BP and BMI in childhood has an additive effect in predicting the highest levels of young adult cardiovascular risk. Thus, there should be a focus on treating hypertension in overweight and obese children, in addition to attempting to reduce weight.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.