Evidence map›Paper›PMID 19630946›Full record

ArticleLipids in health and disease2009

Lipid profile in oral submucous fibrosis.

Ravi Mehrotra, Shruti Pandya, Ajay Kumar Chaudhary, Himanshu Pratap Singh, Ritesh Kumar Jaiswal, Mangal Singh, S C Gupta, Mamta Singh

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Oral submucous fibrosis: pathogenesis and therapeutic approaches.International journal of oral science · 2025
    Review
  3. Article
  4. Alteration of Serum Lipid in Oral Sub Mucous Fibrosis in Central India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2018
    Article
  5. Article
  6. Precancerous lesions of oral mucosa.World journal of clinical cases · 2014
    Review
  7. Estimation of serum lipids in patients with Oral Submucous Fibrosis in India.Journal of clinical and experimental dentistry · 2014
    Article
  8. Article
  9. Article
  10. Review
  11. The relationship between serum lipid levels and the risk of oral cancer.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2011
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ravi MehrotraDepartment of Pathology, M.L.N. Medical College, Allahabad, India. rm8509@gmail.com
Shruti Pandya
Ajay Kumar Chaudhary
Himanshu Pratap Singh
Ritesh Kumar Jaiswal
Mangal Singh
S C Gupta
Mamta Singh
Motilal Nehru Medical College · INUniversity of Allahabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges in lipid profile have long been associated with malignancies as lipids play a key role in maintenance of cell integrity. This study evaluated the alterations in extended lipid profile in untreated patients of oral submucous fibrosis (OSMF) and studied the correlation between lipid levels with tobacco consumption. MATERIALS AND

methodsIn this hospital-based study, 65 clinically diagnosed and histopathologically proven patients of OSMF and 42 age and sex matched controls were studied. In these samples serum lipids including: (i) Total cholesterol, (ii) LDL cholesterol (LDLC), (iii) HDL cholesterol (HDLC) (iv) VLDL cholesterol (VLDLC) (v) triglycerides (vi) Apo-A1 (viii) Apo-B and (viii) LPa were analyzed.

resultsA significant decrease in plasma total cholesterol, HDLC and Apo-A1 was observed in patients with OSMF as compared to the controls. Thus an inverse relationship between plasma lipid levels and patients was found in OSMF.

conclusionThe lower levels of plasma cholesterol and other lipid constituents in patients might be due to their increased utilization. The findings strongly warrant an in-depth study of alterations in plasma lipid profile in patients with oral precancerous conditions.

Indexed as

AdolescentAdultApolipoprotein A-IApolipoproteins BCase-Control StudiesChildChronic DiseaseFemaleHumansIndiaLipidsLipoprotein(a)MaleMiddle AgedOral Submucous FibrosisPrecancerous ConditionsApolipoprotein A-IApolipoproteins BLipidsLipoprotein(a)

Identifiers

PMID19630946
PMCPMC2721834
OpenAlexW2003629502

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.