Evidence map›Paper›PMID 19630140›Full record

ReviewInternational journal for parasitology2009

Toxoplasma gondii: 25 years and 25 major advances for the field.

John C Boothroyd

Abstract readReview
In one paragraph

Review in International journal for parasitology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Frontiers in cellular and infection microbiology · 2024
    Article
  8. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I.Genes to cells : devoted to molecular & cellular mechanisms · 2024
    Article
  9. mBio · 2023
    Article
  10. Structural basis of membrane recognition ofLife science alliance · 2022
    Article
  11. Article
  12. Article
  13. Cytologic detection ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
  14. Depletion of Intracellular Glutamine Pools TriggersFrontiers in cellular and infection microbiology · 2021
    Article
  15. Article
  16. Article
  17. A one health approach to vaccines againstFood and waterborne parasitology · 2019
    Review
  18. Frontiers in cellular and infection microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John C BoothroydDepartment of Microbiology and Immunology, Stanford University School of Medicine, CA 94305-5124, USA. john.boothroyd@stanford.edu

Funding

Toxoplasma Rhoptry FunctionR01AI021423 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 1985 to 2018
$7.8M
Strain-specific Host-Pathogen Interactions in ToxoplasmosisR01AI073756 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 2007 to 2016
$4.2M
DEVELOPMENTAL BIOLOGY OF TOXOPLASMAR01AI041014 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 1997 to 2011
$3.8M
ANTIGENS OF TOXOPLASMA GONDII AND THEIR GENESR37AI021423 · NIAID · STANFORD UNIVERSITY · PI BOOTHROYD, JOHN C · 1994 to 2003
$1.6M
NIAID NIH HHS AI21423NIAID NIH HHS AI41014NIAID NIH HHS AI73756NIAID NIH HHS R01 AI021423NIAID NIH HHS R01 AI041014NIAID NIH HHS R01 AI073756NIAID NIH HHS R37 AI021423
6 · The paper itself

Abstract

This article is an attempt to identify the most significant highlights of Toxoplasma research over the last 25 years. It has been a period of enormous progress and the top 25 most significant advances, in the view of this author, are described. These range from the bench to the bedside and represent a tremendous body of work from countless investigators. And, having laid out so much that has been discovered, it is impossible not to also reflect on the challenges that lie ahead. These, too, are briefly discussed. Finally, while every effort has been made to view the field as a whole, the molecular biology background of the author almost certainly will have skewed the relative importance attached to past and future advances. Despite this, it is hoped that the reader will agree with, or at least not disagree too strongly with, most of the choices presented here.

Indexed as

Genome, ProtozoanHost-Parasite InteractionsLife Cycle StagesToxoplasmaToxoplasmosisAnimalsAnti-Infective AgentsCatsChromosome MappingFemaleHumansMiceOrganellesPhylogenyPolymerase Chain ReactionPregnancyAnti-Infective AgentsProtozoan ProteinsProtozoan Vaccines

Identifiers

PMID19630140
PMCPMC2895946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.