Evidence map›Paper›PMID 19629760›Full record

ReviewClinical reviews in allergy & immunology2010

Diagnostic challenges in celiac disease and the role of the tissue transglutaminase-neo-epitope.

Torsten Matthias, Sascha Pfeiffer, Carlo Selmi, M Eric Gershwin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Cutting-edge issues in celiac disease and in gluten intolerance.Clinical reviews in allergy & immunology · 2012
    Review
  4. Review
  5. The future of autoimmunity.Clinical reviews in allergy & immunology · 2012
    Article
  6. Review
  7. Article
  8. Review
  9. Novel trends in celiac disease.Cellular & molecular immunology · 2011
    Review
  10. A new algorithm for the diagnosis of celiac disease.Cellular & molecular immunology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Torsten MatthiasAESKU.KIPP Institute, Mikroforum Ring 3, 55234 Wendelsheim, Germany. matthias@aesku.com
Sascha Pfeiffer
Carlo Selmi
M Eric Gershwin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of celiac disease (CD) remains a clinical challenge based on the incomplete specificity and sensitivity rates of current non-invasive tests. Furthermore, histological assessments fail to identify all overt cases and, in particular, do not manifest pathognomonic alterations in silent cases. Accordingly, the majority of CD cases are diagnosed with great delay. Recent research into the pathogenesis of CD, allowed us to identify a neo-antigen that appears to be the most promising serological tool for the detection of anti-tissue transglutaminase as well as anti-gliadin antibodies.

Indexed as

Celiac DiseaseEnzyme-Linked Immunosorbent AssayEpitopesGliadinHumansSensitivity and SpecificityTransglutaminasesEpitopesGliadinTransglutaminases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.