ReviewMammalian genome : official journal of the International Mammalian Genome Society2009
The gastrointestinal microbiome: a malleable, third genome of mammals.
Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Gut Microbiome in Early Life Stress: A Systematic Review.Nutrients · 2023Pooled it
- Gut microbiome in serious mental illnesses: A systematic review and critical evaluation.Schizophrenia research · 2021Pooled it
- Oleanolic Acid Modulates the Gut-Liver Axis to Alleviate High-Fat Diet-Induced Hepatic Lipid Deposition in Nile Tilapia (Microorganisms · 2026Article
- Genome-resolved analysis of bile acid-metabolizing microbiota in Tibetan antelope (Pantholops hodgsonii).BMC microbiology · 2026Article
- The aging choroid plexus and its relationship with gut dysbiosis and Klotho decline: possible intervention strategies.GeroScience · 2025Review
- Analysis of the gut microbiome in sled dogs reveals glucosamine- and activity-related effects on gut microbial composition.Frontiers in veterinary science · 2024Article
- Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health.Frontiers in nutrition · 2022Article
- A Faithful Gut: Core Features of Gastrointestinal Microbiota of Long-Distance Migratory Bats Remain Stable despite Dietary Shifts Driving Differences in Specific Bacterial Taxa.Microbiology spectrum · 2021Article
- Effects of intestinal lymphatic ligation on intestinal immunity in rats with severe acute pancreatitis.FEBS open bio · 2021Article
- Review
- Gut microbiome in Schizophrenia: Altered functional pathways related to immune modulation and atherosclerotic risk.Brain, behavior, and immunity · 2021Article
- Dysbiosis of intestinal microbiota in critically ill patients and risk of in-hospital mortality.American journal of translational research · 2021Article
- Article
- Review
- Resolution of Crohn's disease.Seminars in immunopathology · 2019Review
- The Burden of Enteropathy and "Subclinical" Infections.Pediatric clinics of North America · 2017Review
- Actors and Factors in the Resolution of Intestinal Inflammation: Lipid Mediators As a New Approach to Therapy in Inflammatory Bowel Diseases.Frontiers in immunology · 2017Review
- Exploring the Microbiome in Heart Failure.Current heart failure reports · 2016Review
- The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse.PloS one · 2014Article
- Diet complexity and estrogen receptor β status affect the composition of the murine intestinal microbiota.Applied and environmental microbiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The nonpathogenic, mutualistic bacteria of the mammalian gastrointestinal tract provide a number of benefits to the host. Recent reports have shown how the aggregate genomes of gastrointestinal bacteria provide novel benefits by functioning as the third major genome in mammals along with the nuclear and mitochondrial genomes. Consequently, efforts are underway to elucidate the complexity of the organisms comprising the unique ecosystem of the gastrointestinal tract, as well as those associated with other epidermal surfaces. The current knowledge of the gastrointestinal microbiome, its relationship to human health and disease with a particular focus on mammalian physiology, and efforts to alter its composition as a novel therapeutic approach are reviewed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.