Evidence map›Paper›PMID 19629073›Full record

ReviewNature reviews. Cancer2009

Assessing cancer risks of low-dose radiation.

Leon Mullenders, Mike Atkinson, Herwig Paretzke, Laure Sabatier, Simon Bouffler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Direct Growth of Transparent Boron Nitride Neutron Shielding Layer for Space Window.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Analyzing Secondary Cancer Risk: A Machine Learning Approach.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. The Future of Radioactive Medicine.Radiation research · 2023
    Review
  18. Cancer risk in adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2023
    Review
  19. Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leon MullendersDepartment of Toxicogenetics, Leiden University Medical Centre, Leiden 2300RC, The Netherlands. L.Mullenders@lumc.nl
Mike Atkinson
Herwig Paretzke
Laure Sabatier
Simon Bouffler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionizing radiation is considered a non-threshold carcinogen. However, quantifying the risk of the more commonly encountered low and/or protracted radiation exposures remains problematic and subject to uncertainty. Therefore, a major challenge lies in providing a sound mechanistic understanding of low-dose radiation carcinogenesis. This Perspective article considers whether differences exist between the effects mediated by high- and low-dose radiation exposure and how this affects the assessment of low-dose cancer risk.

Indexed as

Radiation DosageRadiation, IonizingDNA DamageHumansNeoplasms, Radiation-InducedRisk AssessmentSignal Transduction

Identifiers

PMID19629073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.