Trial reportObesity (Silver Spring, Md.)2009
Exercise improves body fat, lean mass, and bone mass in breast cancer survivors.
Trial report in Obesity (Silver Spring, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 19 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 19 syntheses or guidelines pooled it, 189 citations in OpenAlex.
- Do Combined Resistance and Aerobic Exercise Programs Cause an Interference Effect in Women with Breast Cancer? A Systematic Review and Network Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Which Exercise Prescriptions Improve Physical Fitness in Patients with Breast Cancer Before, During, and Following Treatment? A Systematic Review and Meta-analysis of Randomized Controlled Trials.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Effect of exercise on bone-related outcomes in patients with cancer affected by bone metastases or bone loss: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Pooled it
- Effects of exercise interventions on bone health and body composition in postmenopausal women with breast cancer: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Effectiveness of aerobic exercise intervention on cardiovascular disease risk in female breast cancer: a systematic review with meta-analyses.BMC public health · 2024Pooled it
- The effects of exercise on the bone health of people with cancer: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Pooled it
- Exercise for cancer cachexia in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Optimising weight-loss interventions in cancer patients-A systematic review and network meta-analysis.PloS one · 2021Pooled it
- Body weight management in overweight and obese breast cancer survivors.The Cochrane database of systematic reviews · 2020Pooled it
- Physical activity barriers and resources among black women with a history of breast and endometrial cancer: a systematic review.Journal of cancer survivorship : research and practice · 2020Pooled it
- Interventions for promoting habitual exercise in people living with and beyond cancer.The Cochrane database of systematic reviews · 2018Pooled it
- The effect of exercise on bone mineral density in adult cancer survivors: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Pooled it
- Physical activity for women with breast cancer after adjuvant therapy.The Cochrane database of systematic reviews · 2018Pooled it
- Exercise for improving bone health in women treated for stages I-III breast cancer: a systematic review and meta-analyses.Journal of cancer survivorship : research and practice · 2017Pooled it
- Exercise for women receiving adjuvant therapy for breast cancer.The Cochrane database of systematic reviews · 2016Pooled it
- Effects of training on bone mass in older adults: a systematic review.Sports medicine (Auckland, N.Z.) · 2012Pooled it
- Physical activity for cancer survivors: meta-analysis of randomised controlled trials.BMJ (Clinical research ed.) · 2012Pooled it
- Physical activity interventions to improve daily walking activity in cancer survivors.BMC cancer · 2010Pooled it
- An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2010Pooled it
- Effect of exercise on body composition among women with ovarian cancer.Journal of cancer survivorship : research and practice · 2023Trial
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Given the negative effects of a breast cancer diagnosis and its treatments on body weight and bone mass, we investigated the effects of a 6-month randomized controlled aerobic exercise intervention vs. usual care on body composition in breast cancer survivors. Secondary aims were to examine the effects stratified by important prognostic and physiologic variables. Seventy-five physically inactive postmenopausal breast cancer survivors were recruited through the Yale-New Haven Hospital Tumor Registry and randomly assigned to an exercise (n = 37) or usual care (n = 38) group. The exercise group participated in 150 min/week of supervised gym- and home-based moderate-intensity aerobic exercise. The usual care group was instructed to maintain their current physical activity level. Body composition was assessed at baseline and 6-months through dual-energy X-ray absorptiometry (DXA) by one radiologist blinded to the intervention group of the participants. On an average, exercisers increased moderate-intensity aerobic exercise by 129 min/week over and above baseline levels compared with 45 min/week among usual care participants (P < 0.001). Exercisers experienced decreases in percent body fat (P = 0.0022) and increases in lean mass (P = 0.047) compared with increases in body fat and decreases in lean mass in usual care participants. Bone mineral density (BMD) was also maintained among exercisers compared with a loss among usual care participants (P = 0.043). In summary, moderate-intensity aerobic exercise, such as brisk walking, produces favorable changes in body composition that may improve breast cancer prognosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.