Evidence map›Paper›PMID 19627945›Full record

ReviewPM & R : the journal of injury, function, and rehabilitation2009

Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy.

Chad D Markert, Anthony Atala, Jennifer K Cann, George Christ, Mark Furth, Fabrisia Ambrosio, Martin K Childers

Open access · greenAbstract readReview
In one paragraph

Review in PM & R : the journal of injury, function, and rehabilitation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. ACS nano · 2023
    Article
  3. Article
  4. Article
  5. The Phosphonate Derivative of CInternational journal of molecular sciences · 2021
    Article
  6. Review
  7. Migration of mesenchymal stem cells to tumor xenograft models andInternational journal of medical sciences · 2018
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Coaxing stem cells for skeletal muscle repair.Advanced drug delivery reviews · 2015
    Review
  13. Promise(s) of using mesenchymal stem cells in reproductive disorders.The Indian journal of medical research · 2014
    Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chad D MarkertDepartment of Neurology, School of Medicine, and Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Anthony Atala
Jennifer K Cann
George Christ
Mark Furth
Fabrisia Ambrosio
Martin K Childers
Forest Institute · USWake Forest University · USUniversity of Pittsburgh · US

Funding

MUSCLE RESPONSE TO STRESS IN CANINE MUSCULAR DYSTROPHYK08HD001220 · NICHD · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHILDERS, MARTIN K. · 1999 to 2002
$383k
Leupeptin in a Canine Model of Duchenne Muscular DystrophyR21NS050135 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHILDERS, MARTIN K. · 2005 to 2006
$336k
NICHD NIH HHS K08 HD001220NINDS NIH HHS R21 NS050135
6 · The paper itself

Abstract

Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise for patients with degenerative muscle diseases and a number of other conditions. In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy.

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsDisease Models, AnimalGenetic TherapyHumansMiceMuscular Dystrophy, Duchenne

Identifiers

PMID19627945
PMCPMC2746358
OpenAlexW2068917967

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.