ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2009
Genetic control of soybean seed isoflavone content: importance of statistical model and epistasis in complex traits.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 95 citations in OpenAlex.
- Biosynthesis and metabolic engineering of isoflavonoids in model plants and crops: a review.Frontiers in plant science · 2024Review
- QTL mapping reveals key factors related to the isoflavone contents and agronomic traits of soybean (Glycine max).BMC plant biology · 2023Article
- Genome wide association study to detect genetic regions related to isoflavone content in a mutant soybean population derived from radiation breeding.Frontiers in plant science · 2022Article
- The Soybean High Density 'Forrest' by 'Williams 82' SNP-Based Genetic Linkage Map Identifies QTL and Candidate Genes for Seed Isoflavone Content.Plants (Basel, Switzerland) · 2021Article
- Identification of Potential Gene Regulatory Pathways Affecting the Ratio of Four-Seed Pod in Soybean.Frontiers in genetics · 2021Article
- Increase of isoflavones in the aglycone form in soybeans by targeted crossings of cultivated breeding material.Scientific reports · 2019Article
- Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits.International journal of molecular sciences · 2019Review
- Comprehensive RNA sequencing and co-expression network analysis to complete the biosynthetic pathway of coumestrol, a phytoestrogen.Scientific reports · 2019Article
- Dense genotyping-by-sequencing linkage maps of two Synthetic W7984×Opata reference populations provide insights into wheat structural diversity.Scientific reports · 2019Article
- Acid phosphatase gene GmHAD1 linked to low phosphorus tolerance in soybean, through fine mapping.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Fine-mapping of QTLs for individual and total isoflavone content in soybean (Glycine max L.) using a high-density genetic map.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Detecting the QTL-allele system conferring flowering date in a nested association mapping population of soybean using a novel procedure.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- An R2R3-type MYB transcription factor, GmMYB29, regulates isoflavone biosynthesis in soybean.PLoS genetics · 2017Article
- Detecting the QTL-allele system of seed isoflavone content in Chinese soybean landrace population for optimal cross design and gene system exploration.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Article
- Evaluation of genetic variation among Brazilian soybean cultivars through genome resequencing.BMC genomics · 2016Article
- Exploiting Phenylpropanoid Derivatives to Enhance the Nutraceutical Values of Cereals and Legumes.Frontiers in plant science · 2016Review
- Article
- Genetical genomics of Populus leaf shape variation.BMC plant biology · 2015Article
- Article
- Mapping isoflavone QTL with main, epistatic and QTL × environment effects in recombinant inbred lines of soybean.PloS one · 2015Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A major objective for geneticists is to decipher genetic architecture of traits associated with agronomic importance. However, a majority of such traits are complex, and their genetic dissection has been traditionally hampered not only by the number of minor-effect quantitative trait loci (QTL) but also by genome-wide interacting loci with little or no individual effect. Soybean (Glycine max [L.] Merr.) seed isoflavonoids display a broad range of variation, even in genetically stabilized lines that grow in a fixed environment, because their synthesis and accumulation are affected by many biotic and abiotic factors. Due to this complexity, isoflavone QTL mapping has often produced conflicting results especially with variable growing conditions. Herein, we comparatively mapped soybean seed isoflavones genistein, daidzein, and glycitein by using several of the most commonly used mapping approaches: interval mapping, composite interval mapping, multiple interval mapping and a mixed-model based composite interval mapping. In total, 26 QTLs, including many novel regions, were found bearing additive main effects in a population of RILs derived from the cross between Essex and PI 437654. Our comparative approach demonstrates that statistical mapping methodologies are crucial for QTL discovery in complex traits. Despite a previous understanding of the influence of additive QTL on isoflavone production, the role of epistasis is not well established. Results indicate that epistasis, although largely dependent on the environment, is a very important genetic component underlying seed isoflavone content, and suggest epistasis as a key factor causing the observed phenotypic variability of these traits in diverse environments.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.