ArticleBMC genomics2009
The odorant binding protein gene family from the genome of silkworm, Bombyx mori.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
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Who cites it
122 citing papers in PubMed, 265 citations in OpenAlex.
- Smell perception in normal tension glaucoma patients.Molecular vision · 2010Trial
- Genome-wide identification of olfactory receptor and odorant-binding protein gene families and their roles in Heliothine chemosensory evolution.Insect molecular biology · 2026Article
- Exploring the Olfactory Recognition ofInsects · 2026Article
- Odorant-binding proteins and chemosensory proteins in insects: structural insights, functional plasticity, and prospects for targeted pest management.Molecular biology reports · 2026Review
- Sequence and structure analysis for chemosensory proteins and odorant-binding proteins in Nilaparvata lugens (Hemiptera: Delphacidae).Journal of insect science (Online) · 2026Article
- Integrating electrophysiology, behavioral response, and docking studies to decipher odorant-binding protein function in the brinjal shoot and fruit borer, Leucinodes orbonalis Guenee.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Article
- Male-derived PBP4 is essential for sperm competition by mediating sperm motility in moths.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Cloning, Expression, and Odorant Binding Characteristics of the Chemosensory Protein 1 in Asecodes hispinarum, a Parasitoid of the Coconut Leaf Beetle.Journal of chemical ecology · 2025Article
- Identification and Functional Disparity of Pheromone-Binding Proteins from Tomato LeafminerJournal of agricultural and food chemistry · 2025Article
- Transcriptomic Analysis and Comparative Analysis of Gene Families Related to Environmental Adaptation in Two Grylloblattodea Species:Ecology and evolution · 2025Article
- TabsPBP2, a Pheromone-Binding Protein Highly Expressed in Male Antennae ofBiomolecules · 2025Article
- Insight into the Relationships Between Chemical, Protein and Functional Variables in the PBP/GOBP Family in Moths Based on Machine Learning.International journal of molecular sciences · 2025Article
- Genome-Wide Identification and Expression Profiling of Odorant-Binding Protein Genes in the Bean Flower ThripsInsects · 2025Article
- Pheromone-Binding Protein 1 Performs a Dual Function for Intra- and Intersexual Signaling in a Moth.International journal of molecular sciences · 2024Article
- Gut dysbacteriosis induces expression differences in the adult head transcriptome of Spodoptera frugiperda in a sex-specific manner.BMC microbiology · 2023Article
- Article
- A supergene in seaweed flies modulates male traits and female perception.Proceedings. Biological sciences · 2023Article
- Odorant-Binding Proteins and Chemosensory Proteins inInternational journal of molecular sciences · 2023Article
- Article
62 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChemosensory systems play key roles in the survival and reproductive success of insects. Insect chemoreception is mediated by two large and diverse gene superfamilies, chemoreceptors and odorant binding proteins (OBPs). OBPs are believed to transport hydrophobic odorants from the environment to the olfactory receptors.
resultsWe identified a family of OBP-like genes in the silkworm genome and characterized their expression using oligonucleotide microarrays. A total of forty-four OBP genes were annotated, a number comparable to the 57 OBPs known from Anopheles gambiae and 51 from Drosophila melanogaster. As seen in other fully sequenced insect genomes, most silkworm OBP genes are present in large clusters. We defined six subfamilies of OBPs, each of which shows lineage-specific expansion and diversification. EST data and OBP expression profiles from multiple larvae tissues of day three fifth instars demonstrated that many OBPs are expressed in chemosensory-specific tissues although some OBPs are expressed ubiquitously and others exclusively in non-chemosensory tissues. Some atypical OBPs are expressed throughout development. These results reveal that, although many OBPs are chemosensory-specific, others may have more general physiological roles.
conclusionSilkworms possess a number of OBPs genes similar to other insects. Their expression profiles suggest that many OBPs may be involved in olfaction and gustation as well as general carriers of hydrophobic molecules. The expansion of OBP gene subfamilies and sequence divergence indicate that the silkworm OBP family acquired functional diversity concurrently with functional constraints. Further investigation of the OBPs of the silkworm could give insights in the roles of OBPs in chemoreception.
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