ArticleBMC evolutionary biology2009
The evolutionary dynamics of the Helena retrotransposon revealed by sequenced Drosophila genomes.
Article in BMC evolutionary biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 21 citations in OpenAlex.
- Distinct responses to rare codons in selecteLife · 2022Article
- Article
- Helena and BS: Two Travellers between the Genera Drosophila and Zaprionus.Genome biology and evolution · 2018Article
- Genome-wide analysis of transposable elements in the coffee berry borer Hypothenemus hampei (Coleoptera: Curculionidae): description of novel families.Molecular genetics and genomics : MGG · 2017Article
- Identification of misexpressed genetic elements in hybrids between Drosophila-related species.Scientific reports · 2017Article
- VHICA, a New Method to Discriminate between Vertical and Horizontal Transposon Transfer: Application to the Mariner Family within Drosophila.Molecular biology and evolution · 2016Article
- Expression of the Retrotransposon Helena Reveals a Complex Pattern of TE Deregulation in Drosophila Hybrids.PloS one · 2016Article
- Specific activation of an I-like element in Drosophila interspecific hybrids.Genome biology and evolution · 2014Article
- Drosophila embryogenesis scales uniformly across temperature in developmentally diverse species.PLoS genetics · 2014Article
- Genome-wide analysis of intraspecific transposon diversity in yeast.BMC genomics · 2013Article
- Losing identity: structural diversity of transposable elements belonging to different classes in the genome of Anopheles gambiae.BMC genomics · 2012Article
- A snapshot of histone modifications within transposable elements in Drosophila wild type strains.PloS one · 2012Article
- The role of vertical and horizontal transfer in the evolution of Paris-like elements in drosophilid species.Genetica · 2011Article
- Vertical inheritance and bursts of transposition have shaped the evolution of the BS non-LTR retrotransposon in Drosophila.Molecular genetics and genomics : MGG · 2011Article
- Population genomics of transposable elements in Drosophila melanogaster.Molecular biology and evolution · 2011Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have shown that genomes contain a mixture of transposable elements, some of which are still active and others ancient relics that have degenerated. This is true for the non-LTR retrotransposon Helena, of which only degenerate sequences have been shown to be present in some species (Drosophila melanogaster), whereas putatively active sequences are present in others (D. simulans). Combining experimental and population analyses with the sequence analysis of the 12 Drosophila genomes, we have investigated the evolution of Helena, and propose a possible scenario for the evolution of this element.
resultsWe show that six species of Drosophila have the Helena transposable element at different stages of its evolution. The copy number is highly variable among these species, but most of them are truncated at the 5' ends and also harbor several internal deletions and insertions suggesting that they are inactive in all species, except in D. mojavensis in which quantitative RT-PCR experiments have identified a putative active copy.
conclusionOur data suggest that Helena was present in the common ancestor of the Drosophila genus, which has been vertically transmitted to the derived lineages, but that it has been lost in some of them. The wide variation in copy number and sequence degeneration in the different species suggest that the evolutionary dynamics of Helena depends on the genomic environment of the host species.
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