Evidence map›Paper›PMID 19623287›Full record

ArticleDeutsches Arzteblatt international2008

Mastocytosis: a disease of the hematopoietic stem cell.

Hans-Peter Horny, Karl Sotlar, Peter Valent, Karin Hartmann

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Metformin: A potential adjunct for treatment of systemic mastocytosis.The journal of allergy and clinical immunology. Global · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Mastocytosis: from a Molecular Point of View.Clinical reviews in allergy & immunology · 2018
    Review
  11. Myelodysplasia and Mast Cell Leukemia with t(9;22).Case reports in oncological medicine · 2017
    Article
  12. Article
  13. Article
  14. Mast cell function: a new vision of an old cell.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2014
    Review
  15. Article
  16. The differential diagnosis of food intolerance.Deutsches Arzteblatt international · 2009
    Review
  17. Article
  18. Anaesthesia in a patient with mastocytosis.Journal of anaesthesiology, clinical pharmacology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hans-Peter Horny
Karl Sotlar
Peter Valent
Karin Hartmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMastocytosis is an unusual clonal disease of the hematopoietic stem cell.

methodsThis article is based on a selective literature search and on the authors' clinical and pathological experience.

resultsThe clinical manifestations of mastocytosis range from cutaneous mastocytosis, a common, prognostically favorable presentation, to mast cell leukemia, a rare, life-threatening disease. The mediator-induced symptoms usually respond well to H1 antihistamines. Therapeutic standards for cytoreduction in the progressive, systemic forms of mastocytosis are still lacking. DISCUSSION: Because some of the manifestations of mastocytosis are nonspecific and can be mimicked by other diseases, there is a risk of two types of diagnostic error: Mastocytosis may remain undiagnosed when it is actually present, or it may be diagnosed even though morphological and molecular findings rule out mastocytosis. Well-defined criteria should be used to differentiate mastocytosis from other diseases with a similar clinical presentation.

Indexed as

anaphylactic reactiondiagnosisdifferential diagnosismastocytosisurticaria

Identifiers

PMID19623287
PMCPMC2696962

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.