ReviewEuropean journal of clinical nutrition2009
Functional body composition: insights into the regulation of energy metabolism and some clinical applications.
Review in European journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Energy expenditure in head and neck cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Underweight but not underfat: is fat-free mass a key factor in constitutionally thin women?European journal of clinical nutrition · 2021Pooled it
- Is constitutional thinness really different from anorexia nervosa? A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2021Pooled it
- Effect of resistance training on resting metabolic rate and its estimation by a dual-energy X-ray absorptiometry metabolic map.European journal of clinical nutrition · 2015Trial
- Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion.Thyroid : official journal of the American Thyroid Association · 2014Trial
- [Resting Energy Expenditure Assessment in Adults with Obesity: Limitations of Commonly Used Predictive Equations].Problemy endokrinologii · 2026Article
- Beyond GLP-1 Agonists: An Adaptive Ketogenic-Mediterranean Protocol to Counter Metabolic Adaptation in Obesity Management.Nutrients · 2025Review
- Bioimpedance-Estimated Metabolic Age in a Falls Clinic: Associations with Multimorbidity and Physical Frailty.Journal of frailty, sarcopenia and falls · 2025Article
- Observational
- Advances in body composition: a 100-year journey.International journal of obesity (2005) · 2025Review
- Energy Expenditure in Upper Gastrointestinal Cancers: a Scoping Review.Advances in nutrition (Bethesda, Md.) · 2023Article
- Fat and lean mass predict time to hospital readmission or mortality in children treated for complicated severe acute malnutrition in Zimbabwe and Zambia.The British journal of nutrition · 2023Article
- Being a scientist.European journal of clinical nutrition · 2023Review
- Normative reference data for body composition in healthy indigenous populations on the Qinghai-Tibet Plateau.Frontiers in public health · 2022Article
- Association Between Adipose Tissue Proton Density Fat Fraction, Resting Metabolic Rate and FTO Genotype in Humans.Frontiers in endocrinology · 2022Article
- Age-Related Trends in Body Composition among Women Aged 20-80 Years: A Cross-Sectional Study.Journal of obesity · 2022Article
- Metabolic flexibility differs by body composition in adults.Clinical nutrition ESPEN · 2021Article
- Energy Metabolism in Relation to Diet and Physical Activity: A South Asian Perspective.Nutrients · 2021Review
- Artificial intelligence and abdominal adipose tissue analysis: a literature review.Quantitative imaging in medicine and surgery · 2021Review
- Resting Energy Expenditure and Related Factors in 6- to 9-Year-Old Southern African Children of Diverse Population Groups.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The application of advanced methods and techniques and their continuous development enable detailed body composition analyses (BCAs) and modeling of body composition at different levels (e.g., at atomic, molecular, organ-tissue and whole body level). Functional body composition integrates body components into regulatory systems (e.g., on energy balance). Regulation of body weight is closely linked to the mass and function of individual body components. Fat mass is part of the energy intake regulatory feedback system. In addition, fat-free mass (FFM) and fat mass are both determinants of resting energy expenditure (REE). Up to 80% of the variance in energy intake and energy expenditure is explained by body composition. A deviation from normal associations between body components and function suggests a metabolic disequilibrium (e.g., in the REE-FFM relationship or in the plasma leptin-fat mass association) that may occur in response to weight changes and diseases. The concept of functional body composition adds to a more sophisticated view on nutritional status and diseases, as well as to a characterization of biomedical traits that will provide functional evidence relating genetic variants.
Indexed as
Identifiers
19623201What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.