Evidence map›Paper›PMID 19622688›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2009

Asymmetric insular function predicts positional blood pressure in nondemented elderly.

Donald Royall, Jia-Hong Gao, Xia Zhao, Marsha J Polk, Dean Kellogg

Open access · greenAbstract readComparative Study
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donald RoyallDepartment of Psychiatry, The University of Texas Health Science Center, 7703 Floyd Curl Dr., Mail code: 7792, San Antonio, TX 78229-3900, USA. royall@uthscsa.edu
Jia-Hong Gao
Xia Zhao
Marsha J Polk
Dean Kellogg
The University of Texas Health Science Center at San Antonio · US

Funding

Dyspraxia and Autonomic Control in Very Early ADR21NS045121 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI ROYALL, DONALD R · 2003 to 2004
$324k
NINDS NIH HHS NS45121-01A1NINDS NIH HHS R21 NS045121
6 · The paper itself

Abstract

Forty percent of nondemented octogenarians have Braak stages consistent with insular involvement, and may be at risk for "age-related" autonomic dysfunction. The authors examined the association between insular resting cerebral blood flow (rCBF) and cardiovascular functions in 29 nondemented elderly subjects who were highly screened to exclude comorbid cardiovascular disease. Mean insular rCBF was significantly higher on the right than left. However, 35.4% of participants had left dominant rCBF (a high-risk group). Right insular rCBF was significantly lower in the high-risk group. This subset had significantly increased positional drops in systolic blood pressure. While these data cannot address Alzheimer's disease as the specific cause, this possibility is being investigated in other cohorts.

Indexed as

DementiaAgedAged, 80 and overBlood PressureCerebral CortexCerebrovascular CirculationCognitionCohort StudiesFemaleFunctional LateralityHumansMalePosturePredictive Value of TestsPsychomotor PerformanceRisk Factors

Identifiers

PMID19622688
PMCPMC4459127
OpenAlexW2061593998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.