Evidence map›Paper›PMID 19622385›Full record

ReviewMolecular and cellular endocrinology2010

Pineal function: impact of microarray analysis.

David C Klein, Michael J Bailey, David A Carter, Jong-so Kim, Qiong Shi, Anthony K Ho, Constance L Chik, Pascaline Gaildrat, Fabrice Morin, Surajit Ganguly and 7 more

Open access · greenAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

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  14. IGSF9 family proteins.Neurochemical research · 2013
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 7 countries.

David C KleinSection on Neuroendocrinology, Program on Developmental Endocrinology and Genetics, NICHD, National Institutes of Health, Bethesda, MD 20892, USA. kleind@mail.nih.gov
Michael J Bailey
David A Carter
Jong-so Kim
Qiong Shi
Anthony K Ho
Constance L Chik
Pascaline Gaildrat
Fabrice Morin
Surajit Ganguly
Martin F Rath
Morten Møller
David Sugden
Zoila G Rangel
Peter J Munson
Joan L Weller
Steven L Coon
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USUniversity of Alberta · CAUniversity of Copenhagen · DKCardiff University · GBCenter for Information Technology · USInserm · FRInstitute of Molecular Medicine · INNational Institutes of Health · USOriGene (United States) · USPohang University of Science and Technology · KRTexas A&M University · USUniversité de Rouen Normandie · FRUniversity of London · GB

Funding

Statistical And Computational Methods For Gene Expression and Proteomic AnalysisZIACT000266 · CIT · CENTER FOR INFORMATION TECHNOLOGY · PI MUNSON, PETER J · 2009 to 2016
$4.2M
Pineal Regulation: Developmental and Circadian Changes in the Transcriptome ZIAHD008836 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2009 to 2015
$2.4M
Pineal Regulation: Control of arylalkylamine N-acetyltransferaseZ01HD008836 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2007 to 2008
$2.0M
Pineal Regulation: Molecular basis of developmentZIAHD008837 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2009 to 2015
$1.8M
Pineal Regulation: Molecular basis of development Z01HD008837 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2007 to 2008
$1.2M
Pineal Regulation: Neural, transsynaptic and intracellular controlZ01HD008838 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2007 to 2008
$1.2M
Pineal Regulation: Transynaptic And Intracellular MechaZ01HD000095 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID C · 1985 to 2008
$219k
Pineal Regulation: Neuroendocrine immune relationshipZIAHD000095 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KLEIN, DAVID · 2009 to 2010
$149k
Biotechnology and Biological Sciences Research Council BB/D52503X/1CIHRIntramural NIH HHS Z01 HD000095Intramural NIH HHS Z01 HD008836Intramural NIH HHS Z01 HD008837Intramural NIH HHS Z01 HD008838Wellcome Trust
6 · The paper itself

Abstract

Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.

Indexed as

Oligonucleotide Array Sequence AnalysisAnimalsCircadian RhythmHumansMelatoninNeuronsPineal GlandSignal TransductionMelatonin

Identifiers

PMID19622385
PMCPMC3138125
OpenAlexW2067311978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.