ArticleCerebral cortex (New York, N.Y. : 1991)2010
The selectivity and functional connectivity of the anterior temporal lobes.
Article in Cerebral cortex (New York, N.Y. : 1991), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Task-Free Functional Language Networks: Reproducibility and Clinical Application.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Pooled it
- The Roles of Left Versus Right Anterior Temporal Lobes in Conceptual Knowledge: An ALE Meta-analysis of 97 Functional Neuroimaging Studies.Cerebral cortex (New York, N.Y. : 1991) · 2015Pooled it
- Body and object effectors: the organization of object representations in high-level visual cortex reflects body-object interactions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Unraveling the distributed neural code of facial identity through spatiotemporal pattern analysis.Proceedings of the National Academy of Sciences of the United States of America · 2011Trial
- Article
- Bridging Continuous and Discrete Models of the Anterior Temporal Lobe via Cortical Gradients.Research square · 2026Article
- Semantic Representational Strength in the Precuneus and Lateral ATL Predicts Successful Factual Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A functional parcellation of the whole brain in high-functioning individuals with autism spectrum disorder reveals atypical patterns of network organization.Molecular psychiatry · 2025Article
- Spatio-temporal activity of brain electrical sources during processing of abstract social concepts.Social cognitive and affective neuroscience · 2025Article
- Postpartum depression-associated localized neural dysfunction: a voxel-wise meta-analysis of amplitude and synchronization alterations in resting-state fMRI.Frontiers in psychiatry · 2025Review
- Functional connectivity between the uncinate fasciculus and frontotemporal semantic system supports reading comprehension in adolescents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Networks for proper versus common name retrieval: insights from causal mapping and new hypotheses.Brain communications · 2025Review
- A familiar face and person processing area in the human temporal pole.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A neuroanatomical and cognitive model of impaired social behaviour in frontotemporal dementia.Brain : a journal of neurology · 2024Review
- How does the "default mode" network contribute to semantic cognition?Brain and language · 2024Review
- Representational similarity learning reveals a graded multidimensional semantic space in the human anterior temporal cortex.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- The "limbic network," comprising orbitofrontal and anterior temporal cortex, is part of an extended default network: Evidence from multi-echo fMRI.Network neuroscience (Cambridge, Mass.) · 2024Article
- A functional parcellation of the whole brain in individuals with autism spectrum disorder reveals atypical patterns of network organization.bioRxiv : the preprint server for biology · 2023Article
- Impaired social concept processing in persons with autistic-like traits.Scientific reports · 2023Article
- Intracerebral Electrophysiological Recordings to Understand the Neural Basis of Human Face Recognition.Brain sciences · 2023Review
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
One influential account asserts that the anterior temporal lobe (ATL) is a domain-general hub for semantic memory. Other evidence indicates it is part of a domain-specific social cognition system. Arbitrating these accounts using functional magnetic resonance imaging has previously been difficult because of magnetic susceptibility artifacts in the region. The present study used parameters optimized for imaging the ATL, and had subjects encode facts about unfamiliar people, buildings, and hammers. Using both conjunction and region of interest analyses, person-selective responses were observed in both the left and right ATL. Neither building-selective, hammer-selective nor domain-general responses were observed in the ATLs, although they were observed in other brain regions. These findings were supported by "resting-state" functional connectivity analyses using independent datasets from the same subjects. Person-selective ATL clusters were functionally connected with the brain's wider social cognition network. Rather than serving as a domain-general semantic hub, the ATLs work in unison with the social cognition system to support learning facts about others.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.